Petrovichev N N, Iakovlev A Iu
Tsitologiia. 1975 Sep;17(9):1087-9.
This work deals with the previously described process of cellular autophagocytosis in regenerating rat liver. The experimental data obtained indicate that the early appearance of acid phosphatase positive cytoplasmic vacuoles (with diameter more than 2 mu) occur only in a certain portion of the parenchymal cell population (nearly 30% of the total number of hepatocytes) and mainly in the central area of the hepatic lobule. It may be concluded that the observed reaction of the cell vacuolar apparatus concerns hepatocytes that undergo the entry into the mitotic cycle much later than does the main part (ca 60%) of cell population.
这项工作涉及先前描述的大鼠再生肝脏中的细胞自噬过程。获得的实验数据表明,酸性磷酸酶阳性细胞质空泡(直径超过2微米)的早期出现仅发生在实质细胞群体的特定部分(约占肝细胞总数的30%),且主要出现在肝小叶的中央区域。可以得出结论,观察到的细胞液泡装置反应涉及的肝细胞进入有丝分裂周期的时间比细胞群体的主要部分(约60%)晚得多。