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在巴西亚马逊地区苏鲁伊印第安人受试者痰液中检测结核分枝杆菌。

Detection of Mycobacterium tuberculosis in sputum from Suruí Indian subjects, Brazilian Amazon.

作者信息

Basta Paulo Cesar, Oelemann Maraníbia A C, Oelemann Walter M R, Fonseca Leila de Souza, Coimbra Carlos E A

机构信息

Escola Nacional de Saúde Pública Sérgio Arouca, Fiocruz, Rio de Janeiro, RJ, 21041-210, Brasil.

出版信息

Mem Inst Oswaldo Cruz. 2006 Sep;101(6):581-4. doi: 10.1590/s0074-02762006000600001.

DOI:10.1590/s0074-02762006000600001
PMID:17072467
Abstract

This investigation aimed at the detection of Mycobacterium tuberculosis (MTB) in the sputum of Suruí Indian subjects from Amazonia, Brazil. Polymerase chain reaction analyses were positive for 12 samples, five of which were also culture-positive (N = 147). Four MTB genotypes were identified, one of which showed resistance to rifampicin and isoniazid. The study also highlighted one village complex as of particular importance, considering the relatively high number of tuberculosis cases reported and of MTB isolates obtained.

摘要

这项调查旨在检测巴西亚马逊地区苏鲁伊印第安人痰液中的结核分枝杆菌(MTB)。聚合酶链反应分析显示,147份样本中有12份呈阳性,其中5份培养结果也呈阳性。鉴定出四种MTB基因型,其中一种对利福平和异烟肼耐药。考虑到报告的结核病病例数和获得的MTB分离株数量相对较多,该研究还强调了一个特别重要的村庄群落。

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