Burger M, Raskin S, Brockelt S R, Amthor B, Geiss H K, Haas W H
GENETIKA, Laboratory of Genetics, Curitiba, Brazil.
J Clin Microbiol. 1998 Feb;36(2):573-6. doi: 10.1128/JCM.36.2.573-576.1998.
The usefulness of filter paper for preservation of bacterial cells was shown by mixed-linker DNA fingerprint analysis of Mycobacterium tuberculosis isolates from 77 Brazilian patients. DNA fingerprints of samples spotted onto filter paper and conventional culture material were identical. Thus, filter paper specimens analyzed by an amplification-based typing method provide a new resource for epidemiological studies of infectious diseases.
通过对77名巴西患者的结核分枝杆菌分离株进行混合连接子DNA指纹分析,证明了滤纸对保存细菌细胞的有效性。点样于滤纸上的样本与传统培养材料的DNA指纹相同。因此,通过基于扩增的分型方法分析的滤纸标本为传染病的流行病学研究提供了一种新资源。