Sandblom J, Theander S
Department of Medical Physics, University of Göteborg, Sweden.
Bioelectromagnetics. 1991;12(1):9-20. doi: 10.1002/bem.2250120103.
The effects of microwaves on the single-channel kinetics of gramicidin-A channels in lipid bilayer membranes were examined. Attempts were made to separate thermal and athermal effects by accurate measurements of temperature at the site of the membrane and by relating the measured parameters to their previously characterized temperature dependence. It was found that microwave radiation does not affect single-channel conductance or channel life time to a degree that is significantly different from that expected of a purely thermal effect. On the other hand, the rate of channel formation is decreased during exposure, which is opposite to that expected of a purely thermal effect. The mechanism of this effect is discussed in terms of the dimerization process of channel formation.
研究了微波对脂质双分子层膜中短杆菌肽A通道单通道动力学的影响。通过精确测量膜位点的温度，并将测量参数与其先前表征的温度依赖性相关联，试图分离热效应和非热效应。结果发现，微波辐射对单通道电导或通道寿命的影响程度与纯热效应预期的程度没有显著差异。另一方面，在暴露过程中通道形成的速率降低，这与纯热效应预期的情况相反。根据通道形成的二聚化过程讨论了这种效应的机制。
