Alekseev S I, Ziskin M C
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region.
Bioelectromagnetics. 1995;16(2):124-31. doi: 10.1002/bem.2250160209.
The effects of millimeter microwaves in the frequency range of 54-76 GHz on capacitance and conductance of lipid bilayer membranes (BLM) were studied. Some of the membranes were modified by gramicidin A and amphotericin B or by tetraphenylboron anions (TPhB-). The millimeter microwaves were pulse-modulated (PW) at repetition rates ranging from 1 to 100 pps, PW at 1000 pps, or unmodulated continuous waves (CW). The maximum output power at the waveguide outlet was 20 mW. It was found that CW irradiation decreased the unmodified BLM capacitance by 1.2% +/- 0.5%. At the same time, membrane current induced by TPhB- transport increased by 5% +/- 1%. The changes in conductance of ionic channels formed by gramicidin A and amphotericin B were small (0.6% +/- 0.4%). No "resonance-like" effects of mm-wave irradiation on membrane capacitance, ionic channel currents, or TPhB- transport were detected. All changes in membrane capacitance and currents were independent of the modulation employed and were equivalent to heating by approximately 1.1 degrees C.
研究了频率范围为54 - 76 GHz的毫米波对脂质双分子层膜（BLM）电容和电导的影响。部分膜用短杆菌肽A、两性霉素B或四苯基硼阴离子（TPhB-）进行了修饰。毫米波采用脉冲调制（PW），重复频率范围为1至100次/秒、1000次/秒的PW或未调制的连续波（CW）。波导出口处的最大输出功率为20 mW。结果发现，连续波照射使未修饰的BLM电容降低了1.2%±0.5%。同时，由TPhB-转运诱导的膜电流增加了5%±1%。由短杆菌肽A和两性霉素B形成的离子通道的电导变化较小（0.6%±0.4%）。未检测到毫米波照射对膜电容、离子通道电流或TPhB-转运的“类共振”效应。膜电容和电流的所有变化均与所采用的调制方式无关，且相当于大约1.1℃的加热效应。
