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[主动脉瓣及升主动脉重建的适应症、技术及结果]

[Indication, technique, and results of aortic valve and ascending aorta reconstruction].

作者信息

Wittlinger Thomas, Aybek Tayfun, Moritz Anton, Kleine Peter, Martens Sven, Wimmer-Greinecker Gerhard

机构信息

Klinik für Thorax-, Herz- und thorakale Gefässchirurgie, Klinikum der Johann-Wolfgang-Goethe-Universität, Theodor-Stern-Kai 7, 60590 Frankfurt/Main.

出版信息

Herz. 2006 Oct;31(7):676-84. doi: 10.1007/s00059-006-2893-8.

Abstract

Aortic valve replacement is the standard procedure in patients with aortic valve regurgitation (AR). Although long-term results for both biological and mechanical heart valves could be improved, a valve-sparing operation has several advantages especially in young patients. Alterations in the geometry of the aortic root, especially dilatation of the sinutubular junction, are the primary cause of AR in patients with aneurysms of the ascending aorta. In patients with a bicuspid aortic valve, AR is usually caused by a prolapse; with appropriate surgical experience, the prolapse can be corrected and the valve reconstructed. Isolated reconstruction of a tricuspid aortic valve such as decalcification, commissurotomy or plication of ring or leaflets are seldom indicated. The recontstructive techniques for aortic root aneurysms or type A dissection described by David and Yacoub have become routine procedures over the last decade. The long-term clinical results are excellent, and revision and thromboembolism rates are very low. A maximal diameter of the aortic root > 5 cm is indicative for performing the above procedures. This technique has been used in the own clinic since 1996 with excellent clinical and echocardiographic results. Only four of 101 patients operated had a moderate AR during the follow-up period. The reconstruction of a prolapse in a bicuspid aortic valve is possible by using an autologous, fixed pericardial patch, with very good long-term results. By using this surgical technique, two geometrically correct pockets with a broad coaptation zone can be constructed. In 36 of the patients operated in the own clinic, only four patients showed grade I AR. No patient had to undergo reoperation. An aortic valve reconstruction for an isolated leaflet perforation following a healed endocarditis is seldom indicated.In the authors' opinion, valve-sparing reconstruction in cases of aneurysms of the ascending aorta, and for bicuspid valves, represents a promising alternative to prosthetic valve replacement. With low surgical mortality and morbidity, excellent clinical and functional long-term results can be achieved. Furthermore, the lack of the necessity of anticoagulation as well as positive hemodynamic factors argue for a valve-sparing surgical technique. A final evaluation of the method is not possible, however, until long-term follow-up of up to 20 years is available and the positive results have been confirmed.

摘要

主动脉瓣置换术是主动脉瓣反流(AR)患者的标准手术。尽管生物和机械心脏瓣膜的长期效果都有待改善,但保留瓣膜手术有诸多优势,尤其对于年轻患者。主动脉根部几何形状的改变,特别是窦管交界的扩张,是升主动脉瘤患者发生AR的主要原因。在二叶式主动脉瓣患者中,AR通常由脱垂引起;凭借适当的手术经验,脱垂可得到纠正且瓣膜可重建。很少需要对三尖瓣主动脉瓣进行单纯重建,如脱钙、交界切开或瓣环或瓣叶折叠术。大卫(David)和亚库布(Yacoub)描述的主动脉根部瘤或A型夹层的重建技术在过去十年已成为常规手术。长期临床效果良好,翻修率和血栓栓塞率很低。主动脉根部最大直径>5 cm提示需进行上述手术。自1996年起该技术已在本诊所应用,临床和超声心动图结果良好。在随访期间,101例接受手术的患者中只有4例有中度AR。使用自体固定心包补片可重建二叶式主动脉瓣的脱垂,长期效果非常好。通过这种手术技术,可构建两个几何形状正确且有宽贴合区的袋状结构。在本诊所接受手术的36例患者中,只有4例显示I级AR。没有患者需要再次手术。很少需要对感染性心内膜炎愈合后孤立的瓣叶穿孔进行主动脉瓣重建。作者认为,对于升主动脉瘤和二叶式瓣膜病例,保留瓣膜重建是人工瓣膜置换的一个有前景的替代方案。手术死亡率和发病率低,可取得良好的长期临床和功能效果。此外,无需抗凝以及积极的血流动力学因素支持保留瓣膜手术技术。然而,在有长达20年的长期随访且阳性结果得到证实之前,无法对该方法进行最终评估。

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