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布氏杆菌溃疡的风险因素,贝宁

Risk factors for Buruli ulcer, Benin.

作者信息

Debacker Martine, Portaels Frangoise, Aguiar Julia, Steunou Christian, Zinsou Claude, Meyers Wayne, Dramaix Michèle

机构信息

Institute of Tropical Medicine, Antwerp, Belgium.

出版信息

Emerg Infect Dis. 2006 Sep;12(9):1325-31. doi: 10.3201/eid1209.050598.

Abstract

We identified risk factors for Buruli ulcer (BU) in Benin in an unmatched case-control study at the Centre Sanitaire et Nutritionnel Gbemoten in southern Benin. A total of 2,399 persons admitted from 1997 through 2003 and 1,444 unmatched patients with other conditions in 2002 were recruited. Adjusted odds ratios were determined for age, sex, place of residence, Mycobacterium bovis BCG vaccination at birth, type of water for domestic use, and occupation. Children <15 years of age and adults >49 years of age had a higher risk for BU. Use of unprotected water from swamps was associated with increased risk for BU; this association was strongest in adults >49 years of age. Sex was not a risk factor for BU. Our data showed that BU was mainly associated with age, place of residence, and water sources in all age groups. Risk for BU was higher in BCG-vaccinated patients > or =5 years of age.

摘要

在贝宁南部的卫生与营养中心Gbemoten进行的一项非匹配病例对照研究中,我们确定了贝宁布鲁里溃疡(BU)的风险因素。共招募了1997年至2003年期间入院的2399人以及2002年1444名患有其他疾病的非匹配患者。确定了年龄、性别、居住地点、出生时卡介苗接种情况、生活用水类型和职业的调整比值比。15岁以下儿童和49岁以上成年人患布鲁里溃疡的风险更高。使用来自沼泽地的未受保护水源与布鲁里溃疡风险增加有关;这种关联在49岁以上成年人中最为明显。性别不是布鲁里溃疡的风险因素。我们的数据表明,布鲁里溃疡在所有年龄组中主要与年龄、居住地点和水源有关。5岁及以上接种卡介苗的患者患布鲁里溃疡的风险更高。

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