O'Connor K A, Cotter P E, Kingston M, Twomey C, O'Mahony D
South Munster Geriatric Training Scheme, Dept of Geriatric Medicine, Cork University Hospital, Wilton, Cork.
Ir J Med Sci. 2006 Jul-Sep;175(3):28-31. doi: 10.1007/BF03169169.
The combination of ageing, illness, and medications can lead to hyponatraemia or hypernatraemia.
To describe the distribution of plasma sodium levels in older patients admitted to hospital.
We carried out a hospital based cross-sectional study examining 1,511 serum sodium concentrations ([Na+]) among 336 elderly patients and attempted to elucidate the cause(s) of the abnormal serum [Na+].
The study population had a mean age of 81.4. Ninety-two (27.4%) patients had hyponatraemia and seven patients (2.1%) had hypernatraemia during their hospitalisation. The distribution of [Na+] results was towards the lower end of the normal range. The mortality rate of patients with hyponatraemia was 14.1% and that of patients with normal serum [Na+] was 8.9%. Six patients with hypernatraemia died in hospital. Lower respiratory tract infection and medication accounted for the majority of cases.
Deranged [Na+] is common among elderly patients admitted to hospital.
衰老、疾病和药物的综合作用可导致低钠血症或高钠血症。
描述老年住院患者血浆钠水平的分布情况。
我们开展了一项基于医院的横断面研究,检测了336例老年患者的1511份血清钠浓度([Na+]),并试图阐明血清[Na+]异常的原因。
研究人群的平均年龄为81.4岁。92例(27.4%)患者在住院期间发生低钠血症,7例(2.1%)患者发生高钠血症。[Na+]结果分布趋向于正常范围的下限。低钠血症患者的死亡率为14.1%,血清[Na+]正常的患者死亡率为8.9%。6例高钠血症患者在医院死亡。下呼吸道感染和药物是大多数病例的病因。
血清[Na+]紊乱在老年住院患者中很常见。