Liou Miaw-Jene, Lin Jen-Der, Chung Mei-Hsin, Liau Chi-Ting, Hsueh Chuen
Section of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taiwan.
Acta Otolaryngol. 2005 Apr;125(4):438-42. doi: 10.1080/00016480410022822.
Papillary or follicular microcarcinoma of the thyroid comprises 10-20% of all thyroid malignancies. Most of these diseases exhibit slow progression and have a favorable prognosis. Distant metastasis caused by thyroid microcarcinoma is uncommon, and is usually found in the lung or bone. Thyroid microcarcinoma with metastasis to the kidney has not previously been reported. Clinically detectable well-differentiated metastatic thyroid carcinoma to the kidney is rare, and only 16 cases have been reported. Herein we describe a case of metastatic papillary thyroid microcarcinoma to the kidney in a patient with a pelvic fracture and pulmonary metastasis. The patient underwent a total thyroidectomy, radiotherapy, ablation treatment with 131I and thyroxine suppressive therapy. In conclusion, microcarcinoma cannot be ignored. Although uncommon, metastases may arise.
甲状腺乳头状或滤泡状微小癌占所有甲状腺恶性肿瘤的10%-20%。这些疾病大多进展缓慢,预后良好。甲状腺微小癌引起的远处转移并不常见,通常发生在肺或骨。此前尚未有甲状腺微小癌转移至肾脏的报道。临床上可检测到的分化良好的甲状腺癌转移至肾脏的情况罕见,仅有16例报道。在此,我们描述一例骨盆骨折并伴有肺转移的患者发生甲状腺乳头状微小癌转移至肾脏的病例。该患者接受了甲状腺全切术、放疗、131I消融治疗及甲状腺素抑制治疗。总之,微小癌不容忽视。虽然罕见,但仍可能发生转移。