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通过蛋白质组学分析鉴定参与精子活力调节的几种蛋白质。

Identification of several proteins involved in regulation of sperm motility by proteomic analysis.

作者信息

Zhao Chun, Huo Ran, Wang Fu-Qiang, Lin Min, Zhou Zuo-Min, Sha Jia-Hao

机构信息

Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, People's Republic of China.

出版信息

Fertil Steril. 2007 Feb;87(2):436-8. doi: 10.1016/j.fertnstert.2006.06.057. Epub 2006 Oct 30.

DOI:10.1016/j.fertnstert.2006.06.057
PMID:17074334
Abstract

Proteomic technology was used to compare sperm protein expression profiles in asthenozoospermic patients with that of normozoospermic donors and 10 differentially expressed proteins were identified. These proteins may play roles in the regulation of sperm motility, and their characterization could merit further investigation on sperm motility-related male factor infertility.

摘要

蛋白质组学技术被用于比较弱精子症患者与正常精子捐献者的精子蛋白质表达谱，并鉴定出10种差异表达的蛋白质。这些蛋白质可能在精子运动的调节中发挥作用，对它们的特性进行研究可能有助于进一步探讨与精子运动相关的男性因素不育症。

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