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[时间复用立体摄影术:青光眼性视盘萎缩的二维和三维定性及半定量评估]

[Time-multiplexing stereophotography: 2D and 3D qualitative and semiquantitative evaluation of glaucomatous optic disc atrophy].

作者信息

Lehmann M V, Mardin C Y, Lausen B, Reulbach U, Bergua A

机构信息

Département d'Ophtalmologie, Université d'Erlangen, Nürnberg, Allemagne.

出版信息

J Fr Ophtalmol. 2006 Oct;29(8):916-23. doi: 10.1016/s0181-5512(06)70113-9.

Abstract

PURPOSE

Real color documentation of the optic nerve head (ONH) is one of the most important methods in identifying early progression of glaucomatous optic nerve damage. This study qualitatively and semiquantitatively compared the evaluation of ONH photographs, using a 3D time-multiplexing system and conventional 2D photography, visualized on a computer monitor.

PATIENTS AND METHODS

Twelve 15 degrees sequential stereophotographs from the Erlangen Glaucoma Registry were scanned by a SprintScan 35 Plus Film scanner (Polaroid, Waltham, MA, USA) and converted by computer software (3D-PIX, NuVision, McNaughton Inc., Beaverton, OR, USA) in jps format (3D). The same ONH images were shown in 2D and 3D to 22 subjects: 12 residents and ten ophthalmologists and evaluated using a standardized questionnaire.

RESULTS

We observed a significantly better evaluation with stereoscopic pictures for both qualitative parameters (cup depth, visibility of the retinal nerve fibers, and the thinnest location of the neuroretinal rim) and quantitative parameters (c/d ratio and size of the disc, depending on the training level: in 3D better evaluation by the residents, in 2D by the ophthalmologists). With 2D pictures, we found better evaluation of the B zone and the stage of atrophy. Other than the method used for the entire evaluation, there was no significant difference between the groups. For the parameters weighed for clinical importance, the score of correct answers was significantly better with stereoscopic pictures.

CONCLUSION

This study showed a significantly better evaluation of glaucomatous ONH atrophy with 3D images than with 2D pictures, independently of the evaluators' clinical training level. The computer-based evaluation of ONH atrophy using a time-multiplexing system (shutter glasses) may improve the diagnosis of glaucoma patients.

摘要

目的

对视神经乳头(ONH)进行真实色彩记录是识别青光眼性视神经损伤早期进展的最重要方法之一。本研究使用3D时间复用系统和传统2D摄影技术,在计算机显示器上可视化,对视神经乳头照片的评估进行了定性和半定量比较。

患者与方法

从埃尔朗根青光眼登记处获取的12张15度连续立体照片,由SprintScan 35 Plus胶片扫描仪(宝丽来,美国马萨诸塞州沃尔瑟姆)扫描,并通过计算机软件(3D-PIX,NuVision,美国俄勒冈州比弗顿的McNaughton公司)转换为jps格式(3D)。将相同的视神经乳头图像以2D和3D形式展示给22名受试者:12名住院医师和10名眼科医生,并使用标准化问卷进行评估。

结果

我们观察到,对于定性参数(杯深、视网膜神经纤维的可见性以及神经视网膜边缘最薄处)和定量参数(杯盘比和视盘大小,取决于培训水平:住院医师对3D图像的评估更好,眼科医生对2D图像的评估更好),立体照片的评估明显更好。对于2D照片,我们发现对B区和萎缩阶段的评估更好。除了用于整体评估的方法外,两组之间没有显著差异。对于临床重要性加权的参数,立体照片的正确答案得分明显更高。

结论

本研究表明,与2D照片相比,3D图像对视神经性青光眼萎缩的评估明显更好,且与评估者的临床培训水平无关。使用时间复用系统(快门眼镜)对ONH萎缩进行基于计算机的评估可能会改善青光眼患者的诊断。

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