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复杂分子系统进化能力的结构限制

Structural limits for evolutive capacities in complex molecular systems.

作者信息

Bergareche A M, Ostolaza J F

机构信息

Dept. de Logica y Filosofia della Ciencia, Donistia, S. Sebastian, Spain.

出版信息

Riv Biol. 1990;83(2-3):335-47.

PMID:1707552
Abstract

The possibilities of evolution for a system with and without a code of translation from nucleic acids into proteins are evaluated. Our interest is mainly centred on the enzymatic RNA case since this molecule has, at the same time, reproductive and functional properties. After scanning the evolutive capacities of the enzymatic RNAs, including the possibility to play the role of "synthetase" which would match nucleic acids with amino acids as a transition step towards a code, we will try to show that due to their own functional limitative factors, the matching system (code) is necessary. This would be the only way to transform the formal complexity--complexity which has not entered into action before the translation process--into functional information to drive the instructive self-reproductive process. Once this stage is reached, the system could evolve without a limit.

摘要

评估了具有和不具有从核酸到蛋白质翻译密码的系统的进化可能性。我们的兴趣主要集中在酶RNA的情况,因为这种分子同时具有复制和功能特性。在审视了酶RNA的进化能力,包括其作为迈向密码的过渡步骤将核酸与氨基酸匹配的“合成酶”作用的可能性之后,我们将试图表明,由于其自身的功能限制因素,匹配系统(密码)是必要的。这将是把形式复杂性——在翻译过程之前尚未发挥作用的复杂性——转化为驱动指导性自我复制过程的功能信息的唯一途径。一旦达到这个阶段,系统就可以无限制地进化。

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引用本文的文献

1
From records to self-description: the role played by RNA in early evolutive systems.
Acta Biotheor. 1992 Mar;40(1):1-9. doi: 10.1007/BF00046546.