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From records to self-description: the role played by RNA in early evolutive systems.

作者信息

Moreno Bergareche A, Fernández Ostolaza J

机构信息

Departamento de Lógica y Filosofía de la Ciencia, Universidad del País Vasco, San Sebastián, Spain.

出版信息

Acta Biotheor. 1992 Mar;40(1):1-9. doi: 10.1007/BF00046546.

DOI:10.1007/BF00046546
PMID:1378239
Abstract

We study the appearance of genetic information starting from a system where self-reproductive and enzymatic functions are supported by the same sort of molecules. In a first phase, the information must have arisen in the form of rate independent sequences as records of enzymatic functions. Although this stage must have played an important role in evolution, it will be shown how its evolutive capacities were blocked by the impossibility of appearance of geno/phenotype duality. Finally, a logical scheme is proposed for a transition process toward a system with a code offering a simplification of the conditions required from the assumption of a maximum use of the double RNA capacity, both reproductive and enzymatic.

摘要

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Structural limits for evolutive capacities in complex molecular systems.复杂分子系统进化能力的结构限制
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