Armadá F, Romero R, Ortega I, Fonseca A
Servicio de Oftalmología, Hospital Universitario La Paz, Madrid, España.
Arch Soc Esp Oftalmol. 2006 Oct;81(10):603-6. doi: 10.4321/s0365-66912006001000009.
We present two patients with Diffuse Retinal Pigment Epitheliopathy (DRPE) treated with verteporfin photodynamic therapy (PDT). The first patient was treated with PDT because there was foveal involvement. The second patient received PDT because he had multiple recurrences of DRPE with poor resolution following previous argon-laser photocoagulation. Resolution of the lesions occurred in both cases with improvement in visual acuity. No recurrences have been documented at eleven months of follow-up.
The outcomes in our patients were satisfactory. We consider PDT is a safe and effective option, but further randomized studies are necessary to confirm this.
我们介绍了两名接受维替泊芬光动力疗法（PDT）治疗的弥漫性视网膜色素上皮病变（DRPE）患者。第一名患者因黄斑受累而接受PDT治疗。第二名患者接受PDT治疗是因为他的DRPE多次复发，且在先前的氩激光光凝治疗后分辨率较差。两例患者的病变均得到缓解，视力有所改善。在随访的11个月中，未记录到复发情况。
我们患者的治疗结果令人满意。我们认为PDT是一种安全有效的选择，但需要进一步的随机研究来证实这一点。
