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单相抑郁症患者对愤怒面孔的注意偏向

Attentional biases for angry faces in unipolar depression.

作者信息

Leyman Lemke, De Raedt Rudi, Schacht Rik, Koster Ernst H W

机构信息

Ghent University, Ghent, Belgium.

出版信息

Psychol Med. 2007 Mar;37(3):393-402. doi: 10.1017/S003329170600910X. Epub 2006 Nov 1.

Abstract

BACKGROUND

Past research has demonstrated that depression is associated with dysfunctional processing of emotional information. Recent studies demonstrate that a bias in the attentional processing of negative information may be an important cognitive vulnerability factor underlying the onset and maintenance of depression. However, to date, the nature of this attentional bias is still poorly understood and further exploration of this topic to advance current knowledge of attentional biases in depression seems imperative.

METHOD

This study examined attentional biases for angry facial expressions presented for 1000 ms in 20 patients with major depressive disorder (MDD) and 20 non-depressed control participants (NC) matched for age and gender using an emotional modification of the Exogenous Cueing task.

RESULTS

Patients with MDD showed maintained attention for angry faces compared with neutral faces. In comparison with non-depressed participants they showed a stronger attentional engagement for angry faces. In contrast, the NC group directed attention away from angry faces, more rapidly disengaging their attention compared with neutral faces.

CONCLUSIONS

This pattern of results supports the assumption that MDD is characterized by deficits in the attentional processing of negative, interpersonal information and suggests a 'protective' bias in non-depressed individuals. Implications in relation to previous research exploring cognitive and interpersonal functioning in depression are discussed.

摘要

背景

以往研究表明,抑郁症与情绪信息处理功能障碍有关。近期研究表明,对负面信息的注意力加工偏差可能是抑郁症发病和维持的一个重要认知脆弱因素。然而,迄今为止,这种注意力偏差的本质仍知之甚少,进一步探索这一主题以推进对抑郁症中注意力偏差的现有认识似乎势在必行。

方法

本研究使用对外源性线索任务的情绪修改版本,对20名重度抑郁症(MDD)患者和20名年龄及性别匹配的非抑郁对照参与者(NC)进行测试,考察他们对呈现1000毫秒的愤怒面部表情的注意力偏差。

结果

与中性面孔相比,MDD患者对愤怒面孔保持关注。与非抑郁参与者相比,他们对愤怒面孔表现出更强的注意力投入。相比之下,NC组将注意力从愤怒面孔上移开,与中性面孔相比,他们能更快地转移注意力。

结论

这种结果模式支持了以下假设,即MDD的特征是在对负面人际信息的注意力加工方面存在缺陷,并表明非抑郁个体存在一种“保护性”偏差。讨论了与先前探索抑郁症认知和人际功能的研究相关的意义。

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