单侧压迫性视神经病变中的多焦视觉诱发电位
Multifocal visual-evoked potential in unilateral compressive optic neuropathy.
作者信息
Semela Linda, Yang E Bo, Hedges Thomas R, Vuong Laurel, Odel Jeffery G, Hood Donald C
机构信息
New England Eye Center, Tufts New England Medical Center, Tufts University, Boston, MA 02111, USA.
出版信息
Br J Ophthalmol. 2007 Apr;91(4):445-8. doi: 10.1136/bjo.2006.097980. Epub 2006 Oct 31.
AIM
To evaluate the effects of unilateral compressive optic neuropathy on amplitude and latency of multifocal visual evoked potentials (mfVEPs).
METHODS
Static automated perimetry and mfVEP recordings were obtained from six patients with presumed meningiomas affecting one optic nerve. Monocular and interocular amplitude and latency analyses were performed and compared with normal control subjects.
RESULTS
The change in the mfVEP amplitude agreed with visual field findings with regard to topography and severity of deviation from normal. The delay in recordable responses from affected eyes ranged from 7.6 to 20.7 ms (interocular analysis) and 7.9 to 13.9 ms (monocular analysis).
CONCLUSIONS
Compressive optic neuropathy decreases the amplitude and increases the latency of the mfVEP. The changes in latency were similar to those seen in optic neuritis but larger than those in ischaemic optic neuropathy and glaucoma.
目的
评估单侧压迫性视神经病变对多焦视觉诱发电位（mfVEP）波幅和潜伏期的影响。
方法
对6例疑似患有影响单眼视神经的脑膜瘤患者进行了静态自动视野检查和mfVEP记录。进行了单眼和双眼间波幅及潜伏期分析，并与正常对照受试者进行比较。
结果
mfVEP波幅的变化在地形图以及与正常偏差的严重程度方面与视野检查结果一致。患眼可记录反应的延迟时间在7.6至20.7毫秒之间（双眼间分析）以及7.9至13.9毫秒之间（单眼分析）。
结论
压迫性视神经病变会降低mfVEP的波幅并增加其潜伏期。潜伏期的变化与视神经炎所见相似，但大于缺血性视神经病变和青光眼。
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