Grandin Wilson, Westwood Tony, Lagerdien Kashifa, King Maylene Shung
Children's Institute, University of Cape Town, South Africa.
S Afr Med J. 2006 Sep;96(9 Pt 2):964-8.
The availability of cause-specific mortality data for children in South Africa is limited. Hospital-based data have the potential to contribute to understanding of the causation of childhood death in South Africa. The objectives of the study were to gain insights into the causes of death in a South African children's hospital.
Prospective, descriptive study of death notification forms.
Red Cross War Memorial Children's Hospital, Cape Town.
Data from 1999 to 2003 were analysed by direct and underlying causes of death (using a modified Global Burden of Diseases (GBD) classification) and demographic variables. Death rates per 1 000 hospital admissions were calculated for certain common causes of death. Seasonal correlates of mortality were examined.
There were 1 978 deaths. The number of deaths per year increased by 11.4% over the period. The death rate rose from 15.9 to 18.4 per 1 000 admissions from 1999 to 2002, declining to 17.4/1 000 in 2003. The death rate was higher for females than for males (18.4/1 000 versus 17.6/1 000, p = 0.007). Sixty per cent of deaths occurred in children less than 1 year old. GBD group I diseases (infectious, nutritional, perinatal) accounted for the greatest proportion of deaths (58.6%), followed by noncommunicable diseases (29.1%), and injuries (7.9%). HIV/AIDS accounted for 60% of infectious deaths (31.6% of all deaths). Diarrhoea-related mortality was 3 times higher in summer than in winter. Congenital conditions dominated GBD group II (57.5%).
The analysis shows the value of routinely recording data on childhood hospital deaths. The results mirror those of the South African Medical Research Council's Burden of Disease studies but also reflect the hospital's tertiary functions. Female children were at higher risk of death. Childhood HIV-related deaths are a major challenge to the health system.
南非儿童特定病因死亡率数据有限。基于医院的数据有助于了解南非儿童死亡的原因。本研究的目的是深入了解一家南非儿童医院的死亡原因。
对死亡通知单进行前瞻性描述性研究。
开普敦红十字战争纪念儿童医院。
按直接死因和根本死因(采用改良的全球疾病负担(GBD)分类法)以及人口统计学变量对1999年至2003年的数据进行分析。计算了某些常见死因每1000例住院患者的死亡率。研究了死亡率的季节相关性。
共1978例死亡。在此期间,每年的死亡人数增加了11.4%。1999年至2002年,每1000例住院患者的死亡率从15.9升至18.4,2003年降至17.4/1000。女性的死亡率高于男性(18.4/1000对17.6/1000,p = 0.007)。60%的死亡发生在1岁以下儿童。GBD第一组疾病(传染病、营养性疾病、围产期疾病)占死亡总数的比例最大(58.6%),其次是非传染性疾病(29.1%)和伤害(7.9%)。艾滋病毒/艾滋病占传染性疾病死亡的60%(占所有死亡的31.6%)。夏季腹泻相关死亡率比冬季高3倍。先天性疾病在GBD第二组中占主导地位(57.5%)。
分析表明了常规记录儿童医院死亡数据的价值。结果与南非医学研究理事会的疾病负担研究结果一致,但也反映了该医院的三级医疗功能。女童死亡风险更高。儿童艾滋病毒相关死亡是卫生系统面临的重大挑战。