（±）-吗啡的全合成
Total synthesis of (+/-)-morphine.
作者信息
Uchida Kenji, Yokoshima Satoshi, Kan Toshiyuki, Fukuyama Tohru
机构信息
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
出版信息
Org Lett. 2006 Nov 9;8(23):5311-3. doi: 10.1021/ol062112m.
PMID:17078705
Abstract
[Structure: see text] The morphinan skeleton was effectively synthesized by an intramolecular Mannich-type reaction. Further transformation led to total synthesis of morphine.
摘要
[结构：见正文] 通过分子内曼尼希型反应有效地合成了吗啡喃骨架。进一步的转化导致了吗啡的全合成。
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