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骨打压植骨术治疗膝关节皮质类固醇相关性骨坏死

Bone impaction grafting for corticosteroid-associated osteonecrosis of the knee.

作者信息

Rijnen Wim H C, Luttjeboer Jaap S, Schreurs B Willem, Gardeniers Jean W M

出版信息

J Bone Joint Surg Am. 2006 Nov;88 Suppl 3:62-8. doi: 10.2106/JBJS.F.00462.

Abstract

BACKGROUND

Osteonecrosis of the distal portion of the femur produces a segment of dead bone in the weight-bearing portion of the femoral condyle, frequently associated with subchondral fracture and collapse and eventually resulting in secondary osteoarthritis. Treatment of these late stages of osteonecrosis in the knee can be problematic. The purpose of the present study was to evaluate a new surgical technique in which the subchondral osteonecrotic lesion is removed. The bone defect is then reconstructed with impacted bone grafts to prevent collapse and/or to regain distal femoral sphericity.

METHODS

In this prospective, one-surgeon study, nine consecutive knees in six patients were studied, all of which had extensive corticosteroid-associated osteonecrotic lesions of the femoral condyles. Six knees had collapsed lesions when they were initially treated. The mean age of the patients was thirty-one years. Both the clinical and radiographic outcomes were assessed at a minimal follow-up time of two years.

RESULTS

At a mean follow-up time of fifty-one months, none of the reconstructed knees had been converted to a total knee prosthesis. The objective Knee Society score improved from a mean of 63 to 89 points. The functional Knee Society score improved from a mean of 19 to 81 points. During the follow-up period, there was no progression of collapse observed; however, three knees showed early signs of osteoarthritis. Clinical success was achieved in six of eight knees, and radiographic success was achieved in seven of nine knees.

CONCLUSIONS

At the time of writing (at the time of midterm follow-up), this method appears attractive as a joint-preserving procedure. It is a relatively simple procedure that is not likely to interfere with future knee procedures. It appears that this technique can be effective in knees with collapse of the femoral condyle, and it may delay the need for a total knee arthroplasty.

LEVEL OF EVIDENCE

Therapeutic Level IV. See Instructions to Authors on jbjs.org for a complete description of levels of evidence.

摘要

背景

股骨远端骨坏死会在股骨髁的负重部位产生一段死骨,常伴有软骨下骨折和塌陷,最终导致继发性骨关节炎。膝关节这些晚期骨坏死的治疗可能存在问题。本研究的目的是评估一种新的手术技术,即切除软骨下骨坏死病变。然后用嵌压植骨重建骨缺损,以防止塌陷和/或恢复股骨远端的球形度。

方法

在这项由一位外科医生进行的前瞻性研究中,对6例患者的9个连续膝关节进行了研究,所有膝关节均有广泛的与皮质类固醇相关的股骨髁骨坏死病变。6个膝关节在初次治疗时存在塌陷病变。患者的平均年龄为31岁。在至少两年的随访时间里评估临床和影像学结果。

结果

平均随访51个月时,所有重建的膝关节均未转换为全膝关节假体。膝关节协会客观评分从平均63分提高到89分。膝关节协会功能评分从平均19分提高到81分。在随访期间,未观察到塌陷进展;然而,3个膝关节出现了早期骨关节炎迹象。8个膝关节中有6个获得临床成功,9个膝关节中有7个获得影像学成功。

结论

在撰写本文时(中期随访时),这种方法作为一种保留关节的手术似乎很有吸引力。这是一种相对简单的手术,不太可能干扰未来的膝关节手术。看来这种技术对股骨髁塌陷的膝关节可能有效,并且可能会推迟全膝关节置换术的需求。

证据水平

治疗水平IV。有关证据水平的完整描述,请参阅jbjs.org上的作者指南。

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