• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

番木瓜籽提取物对小鼠精子的毒理学效应。

Toxicological effects of Carica papaya seed extract on spermatozoa of mice.

作者信息

Verma R J, Nambiar Deepa, Chinoy N J

机构信息

Department of Zoology, University School of Sciences, Gujarat University, Ahmedabad-380009, India.

出版信息

J Appl Toxicol. 2006 Nov-Dec;26(6):533-5. doi: 10.1002/jat.1173.

DOI:10.1002/jat.1173
PMID:17080407
Abstract

Investigations were carried out on epididymal spermatozoa of male mice to study the effects of high dosages (100, 200 and 300 mg kg(-1) bwt) of aqueous Carica papaya seed extract. The results revealed a significant dosedependent suppression of cauda epididymal sperm motility coinciding with a decrease in sperm count and viability. When tested 45 days after the withdrawal of treatment, complete normalcy was restored, proving that the induced effects were transient.

摘要

对雄性小鼠的附睾精子进行了研究,以探讨高剂量(100、200和300毫克/千克体重)番木瓜籽水提取物的影响。结果显示,附睾尾部精子活力受到显著的剂量依赖性抑制,同时精子数量和活力下降。在停止治疗45天后进行测试时,完全恢复了正常,证明诱导效应是短暂的。

相似文献

1
Toxicological effects of Carica papaya seed extract on spermatozoa of mice.番木瓜籽提取物对小鼠精子的毒理学效应。
J Appl Toxicol. 2006 Nov-Dec;26(6):533-5. doi: 10.1002/jat.1173.
2
Efficacy trial on the purified compounds of the seeds of Carica papaya for male contraception in albino rat.番木瓜种子纯化化合物对白化大鼠雄性避孕作用的功效试验。
Reprod Toxicol. 2005 May-Jun;20(1):135-48. doi: 10.1016/j.reprotox.2004.11.015.
3
Chloroform extract of Carica papaya seeds induces long-term reversible azoospermia in langur monkey.番木瓜种子的氯仿提取物可诱导叶猴出现长期可逆性无精子症。
Asian J Androl. 2002 Mar;4(1):17-26.
4
Toxicological investigations on the methanol sub-fraction of the seeds of Carica papaya as a male contraceptive in albino rats.番木瓜种子甲醇亚组分作为白化大鼠雄性避孕药的毒理学研究。
Reprod Toxicol. 2006 Oct;22(3):461-8. doi: 10.1016/j.reprotox.2006.01.002. Epub 2006 Mar 3.
5
Antifertility effects of aqueous extract of Carica papaya seeds in male rats.番木瓜种子水提取物对雄性大鼠的抗生育作用。
Planta Med. 1994 Oct;60(5):400-4. doi: 10.1055/s-2006-959518.
6
Human sperm immobilization effect of Carica papaya seed extracts: an in vitro study.番木瓜种子提取物对人类精子的制动作用:一项体外研究。
Asian J Androl. 2000 Jun;2(2):103-9.
7
The effect of crude extract of the bark of Carica papaya on the seminiferous tubules of male Sprague-Dawley rats.番木瓜树皮粗提物对雄性斯普拉格-道利大鼠生精小管的影响。
Niger Postgrad Med J. 2002 Dec;9(4):205-9.
8
Sperm motility inhibitory effect of the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in langur monkey, Presbytis entellus entellus.番木瓜种子氯仿提取物的苯色谱馏分对长尾叶猴(Presbytis entellus entellus)精子活力的抑制作用
Asian J Androl. 2008 Mar;10(2):298-306. doi: 10.1111/j.1745-7262.2008.00331.x. Epub 2007 Dec 20.
9
Antifertility investigations on the crude chloroform extract of Carica papaya Linn. seeds in male albino rats.番木瓜种子粗氯仿提取物对雄性白化大鼠的抗生育研究。
Indian J Exp Biol. 1992 Nov;30(11):1051-5.
10
Effect of papaya seed extract on microenvironment of cauda epididymis.番木瓜籽提取物对附睾尾部微环境的影响。
Asian J Androl. 2001 Jun;3(2):143-6.

引用本文的文献

1
Comprehensive Review on Fruit Seeds: Nutritional, Phytochemical, Nanotechnology, Toxicity, Food Biochemistry, and Biotechnology Perspective.水果种子的综合综述:营养、植物化学、纳米技术、毒性、食品生物化学和生物技术视角。
Appl Biochem Biotechnol. 2024 Jul;196(7):4472-4643. doi: 10.1007/s12010-023-04674-9. Epub 2023 Sep 27.
2
Toxicological evaluation of the aqueous stem bark extract of Bridelia ferruginea (Euphorbiaceae) in rodents.锈毛土蜜树(大戟科)茎皮水提取物在啮齿动物中的毒理学评价
Interdiscip Toxicol. 2015 Jun;8(2):89-98. doi: 10.1515/intox-2015-0014.
3
In Vivo Antiprotozoal Activity of the Chloroform Extract from Carica papaya Seeds against Amastigote Stage of Trypanosoma cruzi during Indeterminate and Chronic Phase of Infection.
体内抗原生动物活性的氯仿提取物从木瓜种子对在不确定和慢性期感染的克氏锥虫的无鞭毛体阶段。
Evid Based Complement Alternat Med. 2014;2014:458263. doi: 10.1155/2014/458263. Epub 2014 Sep 8.
4
Phytochemical and antifungal profiles of the seeds of carica papaya L.番木瓜种子的植物化学成分及抗真菌特性
Indian J Pharm Sci. 2011 Jul;73(4):447-51. doi: 10.4103/0250-474X.95648.