Noctor Graham
Institut de Biotechnologie des Plantes, UMR CNRS 8618, Université de Paris XI, 91405 Orsay cedex, France.
Plant Cell Environ. 2006 Mar;29(3):409-25. doi: 10.1111/j.1365-3040.2005.01476.x.
Plant growth and development are driven by electron transfer reactions. Modifications of redox components are both monitored and induced by cells, and are integral to responses to environmental change. Key redox compounds in the soluble phase of the cell are NAD, NADP, glutathione and ascorbate--all of which interact strongly with reactive oxygen. This review takes an integrated view of the NAD(P)-glutathione-ascorbate network. These compounds are considered not as one-dimensional 'reductants' or 'antioxidants' but as redox couples that can act together to condition cellular redox tone or that can act independently to transmit specific information that tunes signalling pathways. Emphasis is placed on recent developments highlighting the complexity of redox-dependent defence reactions, and the importance of interactions between the reduction state of soluble redox couples and their concentration in mediating dynamic signalling in response to stress. Signalling roles are assessed within the context of interactions with reactive oxygen, phytohormones and calcium, and the biochemical reactions through which redox couples could be sensed are discussed.
植物的生长和发育由电子转移反应驱动。细胞会监测并诱导氧化还原成分的变化，这些变化是植物对环境变化做出响应所不可或缺的。细胞可溶性相中关键的氧化还原化合物有烟酰胺腺嘌呤二核苷酸（NAD）、烟酰胺腺嘌呤二核苷酸磷酸（NADP）、谷胱甘肽和抗坏血酸——所有这些化合物都与活性氧发生强烈相互作用。本综述对NAD(P)-谷胱甘肽-抗坏血酸网络进行了综合阐述。这些化合物并非被视为一维的“还原剂”或“抗氧化剂”，而是被看作氧化还原对，它们既能共同作用来调节细胞氧化还原状态，也能独立发挥作用来传递特定信息，从而调节信号通路。重点在于近期的研究进展，这些进展突出了氧化还原依赖性防御反应的复杂性，以及可溶性氧化还原对的还原状态与其浓度之间的相互作用在介导应激动态信号传导中的重要性。在与活性氧、植物激素和钙相互作用的背景下评估了信号传导作用，并讨论了能够感知氧化还原对的生化反应。
