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《全面综述:发展、生物活性特性及治疗应用》

Comprehensive Review of : Development, Bioactive Properties, and Therapeutic Applications.

作者信息

Sharara Aya, Badran Adnan, Hijazi Akram, Albahri Ghosoon, Bechelany Mikhael, Mesmar Joelle Edward, Baydoun Elias

机构信息

Plateforme de Recherche et D'Analyse en Sciences de L'Environnement (EDST-PRASE), Beirut P.O. Box 6573/14, Lebanon.

Department of Nutrition, University of Petra, Amman P.O. Box 961343, Jordan.

出版信息

Pharmaceuticals (Basel). 2024 Jun 27;17(7):848. doi: 10.3390/ph17070848.

DOI:10.3390/ph17070848
PMID:39065699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11279937/
Abstract

Plants are being researched as potential sources of novel drugs, which has led to a recent acceleration in the discovery of new bioactive compounds. Research on tissue culture technology for the synthesis and processing of plant compounds has skyrocketed, surpassing all expectations. These plants can be bought either raw or as extracts, where some of the chemicals are extracted by mashing the plant in water, alcohol, or another solvent. The use of herbal medicine may open new chances for reducing the onset of infections and treating different diseases including cancer. A perennial plant that blooms in the winter, , is one of the most widely used potted flowers in many nations. Alkaloids, flavonoids, phenols, tannins, saponins, sterols, and glycosides are the main active components of . Analgesic, cytotoxic, antioxidant, antimicrobial, and anti-inflammatory properties have all been demonstrated as potential effects of various extracts of tubers. However, the use of this medicinal plant in official medicine will require further research in the areas of pharmacology. Furthermore, it is necessary to create standard operating procedures for a crude herbal medication. In this regard, this review aims to highlight the key characteristics of the plant, such as its various parts, species, stages of development, and geographic range; pinpoint its intriguing bioactivities, its antioxidant, anti-inflammatory, and its anti-cancerous effects; and ascertain its potential medicinal uses and the main future perspectives.

摘要

植物正作为新型药物的潜在来源进行研究,这导致了近期新生物活性化合物发现的加速。关于植物化合物合成与加工的组织培养技术研究激增,远超所有预期。这些植物可以以原材料或提取物的形式购买,其中一些化学物质是通过将植物在水、酒精或其他溶剂中捣碎来提取的。草药的使用可能为减少感染的发生和治疗包括癌症在内的不同疾病带来新的机会。一种在冬季开花的多年生植物,是许多国家最广泛使用的盆栽花卉之一。生物碱、黄酮类化合物、酚类、单宁、皂苷、甾醇和糖苷是其主要活性成分。已证明该植物块茎的各种提取物具有镇痛、细胞毒性、抗氧化、抗菌和抗炎特性等潜在作用。然而,这种药用植物在官方医学中的使用需要在药理学领域进行进一步研究。此外,有必要为粗制草药制定标准操作程序。在这方面,本综述旨在突出该植物的关键特征,如其各个部分、物种、发育阶段和地理范围;确定其有趣的生物活性,其抗氧化、抗炎和抗癌作用;并确定其潜在的药用用途和主要的未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/562eacfb73fe/pharmaceuticals-17-00848-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/0f8ace6ddefd/pharmaceuticals-17-00848-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/b322435b8f60/pharmaceuticals-17-00848-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/ce88da242f60/pharmaceuticals-17-00848-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/b0eadfbae99b/pharmaceuticals-17-00848-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/562eacfb73fe/pharmaceuticals-17-00848-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/0f8ace6ddefd/pharmaceuticals-17-00848-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/b322435b8f60/pharmaceuticals-17-00848-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/ce88da242f60/pharmaceuticals-17-00848-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/b0eadfbae99b/pharmaceuticals-17-00848-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/805c/11279937/562eacfb73fe/pharmaceuticals-17-00848-g005.jpg

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