Brookes Jocelyn S, Hagmann Cornelia
Department of Imaging, University College Hospitals NHS Trust London, London, United Kingdom.
J Magn Reson Imaging. 2006 Dec;24(6):1221-8. doi: 10.1002/jmri.20770.
The fetal autopsy involves a series of investigations of the corpse, most of which are noninvasive and acceptable to the majority of parents and their physicians. The value of the perinatal autopsy is manyfold and well established, and the results can provide a basis for parental and family counseling, inform future obstetric management, and provide audit for prenatal care. Many techniques originally developed for diagnosis, such as histology, biochemical tests, photography, x-rays, and cytogenetic karyotyping, have become standard tools in perinatal autopsies. However, there has been an inexorable decline in the autopsy consent rate over the last 30 years due to social and cultural factors, and perhaps ignorance of the benefits to be derived from the examination. Growing evidence suggests that postmortem fetal MRI can assist the pathologist at autopsy, and in many cases can obviate the need for dissection or at least minimize and focus it. For the majority of cases in which no consent for surgical autopsy is given, MRI together with other noninvasive postmortem tests can provide a great deal of the information that was previously available only from autopsy.
胎儿尸检涉及对尸体的一系列检查，其中大多数是非侵入性的，大多数父母及其医生都能接受。围产期尸检的价值是多方面的且已得到充分证实，其结果可为父母和家庭咨询提供依据，为未来的产科管理提供信息，并为产前护理提供审计。许多最初用于诊断的技术，如组织学、生化检测、摄影、x光和细胞遗传核型分析，已成为围产期尸检的标准工具。然而，由于社会和文化因素，以及可能对尸检益处的无知，在过去30年里尸检同意率持续下降。越来越多的证据表明，死后胎儿MRI可以在尸检时协助病理学家，在许多情况下可以避免解剖的需要，或者至少将解剖范围最小化并集中化。对于大多数未同意进行手术尸检的病例，MRI与其他非侵入性死后检测一起可以提供大量以前只能从尸检中获得的信息。
