Evolahti Annika, Hultcrantz Malou, Collins Aila
Department of Clinical Neuroscience, Section of Psychology, Karolinska Institute, Solna, Sweden.
J Psychosom Res. 2006 Nov;61(5):645-52. doi: 10.1016/j.jpsychores.2006.07.022.
The aim of the present study was to investigate whether there is an association between serum cortisol and work-related stress, as defined by the demand-control model in a longitudinal design.
One hundred ten women aged 47-53 years completed a health questionnaire, including the Swedish version of the Job Content Scale, and participated in a psychological interview at baseline and in a follow-up session 2 years later. Morning blood samples were drawn for analyses of cortisol.
Multiple stepwise regression analyses and logistic regression analyses showed that work demands and lack of social support were significantly associated with cortisol.
The results of this study showed that negative work characteristics in terms of high demands and low social support contributed significantly to the biological stress levels in middle-aged women. Participation in the study may have served as an intervention, increasing the women's awareness and thus improving their health profiles on follow-up.
本研究旨在通过纵向设计，调查血清皮质醇与工作相关压力（由需求-控制模型定义）之间是否存在关联。
110名年龄在47至53岁之间的女性完成了一份健康问卷，包括瑞典版工作内容量表，并在基线时参加了一次心理访谈，两年后进行了随访。采集早晨血样用于皮质醇分析。
多元逐步回归分析和逻辑回归分析表明，工作需求和缺乏社会支持与皮质醇显著相关。
本研究结果表明，高需求和低社会支持等负面工作特征对中年女性的生物应激水平有显著影响。参与本研究可能起到了干预作用，提高了女性的意识，从而改善了她们随访时的健康状况。
