Spiegel Jeffrey H, Khodai Naghmeh
Department of Otolaryngology-Head and Neck Surgery, Boston University School of Medicine, Boston, MA 02118, USA.
Am J Otolaryngol. 2006 Nov-Dec;27(6):430-2. doi: 10.1016/j.amjoto.2006.01.014.
The objectives of this case report are to (1) identify clinical presentations of tricholemmoma, (2) discuss the characteristics of Cowden syndrome and the relationship between this syndrome and tricholemmoma, and (3) differentiate tricholemmoma from other superficial cutaneous tumors such as basal cell carcinoma and granulomas.
We present a literature review and a case report.
A literature review of tricholemmoma and a case report of an unusual manifestation of this neoplasm were presented.
Tricholemmoma was first described as a cutaneous neoplasm in 1962. It is associated with the Cowden syndrome and can be misdiagnosed as a more aggressive cutaneous malignancy. We report an unusual case of tricholemmoma presenting as a nasal mass.
Tricholemmoma is described as having a predilection for the head and neck, yet little information has been published about this disorder within the Otolaryngology literature. Otolaryngologist-head and neck surgeons must be familiar with this neoplasm because it can be frequently misdiagnosed as an aggressive cutaneous malignancy and hence can be incorrectly treated. We describe the presentation and diagnosis of tricholemmoma, describe the frequent association of this neoplasm with Cowden syndrome, and report an unusual presentation of tricholemmoma as an intranasal mass.
本病例报告的目的是：（1）确定毛发瘤的临床表现；（2）讨论考登综合征的特征以及该综合征与毛发瘤之间的关系；（3）将毛发瘤与其他浅表皮肤肿瘤如基底细胞癌和肉芽肿相鉴别。
我们进行了文献综述并报告了一例病例。
呈现了关于毛发瘤的文献综述以及该肿瘤一种不寻常表现的病例报告。
毛发瘤于1962年首次被描述为一种皮肤肿瘤。它与考登综合征相关，并且可能被误诊为更具侵袭性的皮肤恶性肿瘤。我们报告了一例表现为鼻腔肿物的不寻常毛发瘤病例。
毛发瘤被描述为好发于头颈部，然而耳鼻喉科文献中关于这种疾病的报道很少。耳鼻喉科头颈外科医生必须熟悉这种肿瘤，因为它常常被误诊为侵袭性皮肤恶性肿瘤，从而可能得到不恰当的治疗。我们描述了毛发瘤的表现和诊断，阐述了该肿瘤与考登综合征的常见关联，并报告了毛发瘤作为鼻内肿物的一种不寻常表现。
