Striegel A M, Myers J B, Sorensen M D, Furness P D, Koyle M A
Department of Urology, Children's Hospital, Denver, Colorado, USA.
J Urol. 2006 Dec;176(6 Pt 1):2632-5. doi: 10.1016/j.juro.2006.08.056.
Persistent unexplained vaginal discharge or bleeding in the pediatric population may be the only manifestation of a serious underlying medical or social problem. Therefore, these symptoms require careful and complete evaluation to identify the primary pathology accurately. We retrospectively reviewed charts of patients who presented for evaluation of persistent vaginal discharge or bleeding to determine if noninvasive imaging was a sensitive means of screening for gynecological pathology.
The records of 24 girls younger than 6 years who presented with vaginal discharge or bleeding were reviewed retrospectively. All patients were evaluated with noninvasive imaging, a pelvic examination while under anesthesia, vaginoscopy and cystoscopy.
Noninvasive imaging was useful in identifying 5 of 7 vaginal foreign bodies. However, noninvasive imaging identified only 2 of 6 malignancies. These malignancies consisted of rhabdomyosarcoma (3 patients) and endodermal sinus tumor (3). Two girls also had benign vaginal mullerian papillomas that were not identified by noninvasive imaging. Noninvasive imaging did not aid in the diagnosis of sexual abuse.
Based on these data, we recommend that all girls younger than 6 years who present with persistent vaginal discharge or bleeding be evaluated with pelvic examination while under anesthesia, to be followed by vaginoscopy and cystoscopy if no readily identifiable pathology is found by simple genital examination alone, regardless of the results of noninvasive imaging studies.
儿科人群中持续存在的不明原因阴道分泌物或出血可能是严重潜在医学或社会问题的唯一表现。因此,这些症状需要仔细且全面的评估,以准确识别主要病理情况。我们回顾性分析了因持续性阴道分泌物或出血前来评估的患者病历,以确定非侵入性成像是否是筛查妇科病理的敏感方法。
回顾性分析了24例6岁以下出现阴道分泌物或出血的女孩的病历。所有患者均接受了非侵入性成像、麻醉下盆腔检查、阴道镜检查和膀胱镜检查。
非侵入性成像有助于识别7例阴道异物中的5例。然而,非侵入性成像仅识别出6例恶性肿瘤中的2例。这些恶性肿瘤包括横纹肌肉瘤(3例患者)和内胚窦瘤(3例)。两名女孩还患有良性阴道苗勒氏乳头状瘤,非侵入性成像未识别出。非侵入性成像对性虐待的诊断没有帮助。
基于这些数据,我们建议对所有6岁以下出现持续性阴道分泌物或出血的女孩在麻醉下进行盆腔检查评估,若仅通过简单的生殖器检查未发现易于识别的病理情况,则随后进行阴道镜检查和膀胱镜检查,无论非侵入性成像研究结果如何。