Sugimoto Chikatoshi, Kobayashi Hideo, Kanoh Soichiro, Motoyoshi Kazuo, Aida Shinsuke
Third Department of Internal Medicine, National Defense Medical College.
Nihon Kokyuki Gakkai Zasshi. 2006 Oct;44(10):738-41.
Chest CT detected a small localized ground glass opacity in the right upper lung in a 52-year-old woman being treated for nocardiosis. A PAS-stain positive material and elevated surfactant level were confirmed in bronchoalveolar lavage fluid, then a diagnosis of pulmonary alveolar proteinosis was established. In early pulmonary alveolar proteinosis with focal opacity, HRCT can demonstrate the substantial findings of alveolar proteinosis such as a crazy-paving appearance or geographic distribution. We should note that alveolar proteinosis in the early stage is easily overlooked and, in addition, nocardiosis might overlap with alveolar proteinosis.
胸部CT在一名正在接受诺卡菌病治疗的52岁女性患者的右上肺发现了一个小的局限性磨玻璃影。支气管肺泡灌洗 fluid中证实了PAS染色阳性物质和表面活性剂水平升高,随后确诊为肺泡蛋白沉积症。在早期伴有局灶性opacity的肺泡蛋白沉积症中,HRCT可以显示肺泡蛋白沉积症的实质性表现,如铺路石样外观或地图状分布。我们应该注意到,早期肺泡蛋白沉积症很容易被忽视,此外,诺卡菌病可能与肺泡蛋白沉积症重叠。