Zhou Qi, Li Shaonan, Li Xiaopeng, Wang Wei, Wang Zhiguo
Beijing Hospital, National Center for Clinical Laboratories, Beijing, PR China.
Clin Chem Lab Med. 2006;44(11):1363-6. doi: 10.1515/CCLM.2006.251.
The purpose of an external quality assessment (EQA) is to evaluate the analytical capability of clinical laboratories, identify differences among the laboratories and improve analytical quality. Our EQA results show that the rates of unsatisfactory performance for thyroid hormone tests were the highest in all of our EQA programs. Therefore, the main purpose of this study was to investigate unsatisfactory results by comparing the analytical values of five routinely used analytical systems.
The Kruskal-Wallis and two-sample Kolmogorov-Smirnov tests were used to identify analytical differences among and between analytical systems, respectively.
The rates of significantly different results compared to the total number of analytical results were 81.1%, 64.5%, 93.3%, 50.0% and 56.7% for free triiodothyronine, total triiodothyronine, free thyroxine, total thyroxine and thyroid-stimulating hormone, respectively.
Relatively large analytical differences between analytical systems were observed, especially when the analytical systems were used to measure free thyroid hormones.
外部质量评估（EQA）的目的是评估临床实验室的分析能力，识别各实验室之间的差异并提高分析质量。我们的EQA结果显示，在所有EQA项目中，甲状腺激素检测的不合格率最高。因此，本研究的主要目的是通过比较五个常规使用的分析系统的分析值来调查不合格结果。
分别使用Kruskal-Wallis检验和双样本Kolmogorov-Smirnov检验来识别分析系统之间以及分析系统内部的分析差异。
游离三碘甲状腺原氨酸、总三碘甲状腺原氨酸、游离甲状腺素、总甲状腺素和促甲状腺激素与分析结果总数相比，显著不同结果的比例分别为81.1%、64.5%、93.3%、50.0%和56.7%。
观察到分析系统之间存在相对较大的分析差异，尤其是当分析系统用于测量游离甲状腺激素时。
