Heusser R, Ender M, Berger-Bächi B, McCallum N
Institute of Medical Microbiology, University of Zurich, 8006 Zurich, Switzerland.
Antimicrob Agents Chemother. 2007 Jan;51(1):390-3. doi: 10.1128/AAC.00921-06. Epub 2006 Nov 6.
A novel staphylococcal cassette chromosome (SCC) mec from a clinical methicillin-resistant Staphylococcus aureus isolate (ST100/CC5) had a mosaic structure, composed of SCC DNA from several different backgrounds. It harbored two complete ccr loci and a new variant of mec complex B, with DeltamecR1 interrupted by the aminoglycoside resistance transposon Tn4001.
一株临床耐甲氧西林金黄色葡萄球菌分离株(ST100/CC5)中的新型葡萄球菌盒式染色体(SCC)mec具有嵌合结构,由来自几种不同背景的SCC DNA组成。它含有两个完整的ccr基因座和一个新的mec复合体B变体,其中DeltamecR1被氨基糖苷类抗性转座子Tn4001中断。