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胎盘部位复旧不全作为产后子宫出血的解剖学原因:综述

Subinvolution of the placental site as an anatomic cause of postpartum uterine bleeding: a review.

作者信息

Weydert Jamie A, Benda Jo Ann

机构信息

Department of Pathology, University of Iowa, Iowa City, USA.

出版信息

Arch Pathol Lab Med. 2006 Oct;130(10):1538-42. doi: 10.5858/2006-130-1538-SOTPSA.

DOI:10.5858/2006-130-1538-SOTPSA
PMID:17090198
Abstract

CONTEXT

Subinvolution of the placental site is an anatomic cause of delayed postpartum uterine bleeding that may be underrecognized by general surgical pathologists.

OBJECTIVE

To review the physiology of uteroplacental arterial development and normal postpartum involution, and to present the characteristic clinical and histopathologic features of subinvolution.

DATA SOURCES

Literature review (MEDLINE via PubMed and Ovid) regarding the pathology and pathophysiology of placental site subinvolution. Review of the clinical and pathologic characteristics of our own institution's previously diagnosed cases of subinvolution from hysterectomy and endomyometrial curettage specimens.

CONCLUSIONS

Surgical pathologists must be aware of the cardinal histopathologic findings of subinvolution, and this diagnosis must be considered in every postpartum curettage or hysterectomy specimen presented to the surgical pathologist. Subinvolution of the placental site is an important diagnosis, as this process implies an idiopathic cause, rather than an iatrogenic cause, of postpartum uterine bleeding. The etiology of placental site subinvolution remains poorly characterized.

摘要

背景

胎盘部位复旧不全是产后子宫出血延迟的一个解剖学原因,普通外科病理学家可能对此认识不足。

目的

回顾子宫胎盘动脉发育及产后正常复旧的生理学过程,并阐述复旧不全的特征性临床和组织病理学特征。

资料来源

关于胎盘部位复旧不全的病理学和病理生理学的文献综述(通过PubMed和Ovid检索MEDLINE)。回顾本机构之前经子宫切除术和子宫内膜刮除术标本诊断为复旧不全的病例的临床和病理特征。

结论

外科病理学家必须了解复旧不全的主要组织病理学表现,对于提交给外科病理学家的每一份产后刮宫或子宫切除标本都必须考虑这一诊断。胎盘部位复旧不全是一项重要诊断,因为这一过程意味着产后子宫出血的原因是特发性的,而非医源性的。胎盘部位复旧不全的病因仍未得到充分阐明。

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