Department of Pathology, Maternal-fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Surg Pathol. 2024 Jun;32(4):787-790. doi: 10.1177/10668969231188905. Epub 2023 Jul 24.
Vascular subinvolution of the placental bed is one of the uncommon but life-threatening forms of secondary postpartum hemorrhage. Studies on subinvolution of the implantation site are sparse and there is a scarcity of practice-based literature for this diagnosis. A 40-year-old woman with vaginal bleeding and light-headedness was admitted a few days after spontaneous abortion. Based on her unstable condition, hysterectomy was done. Pathologic gross evaluation of the uterus identified multiple large and dilated blood vessels, and microscopically, the myometrium showed thrombosis with scattered extravillous trophoblastic cells within the vessel walls. We described this rare case and explored the literature focusing on the pathophysiology and helpful ancillary studies for diagnosing this situation.
胎盘床血管复旧不良是一种罕见但危及生命的产后出血的继发性形式。关于种植部位复旧不良的研究很少，也缺乏针对这种诊断的基于实践的文献。一名 40 岁妇女在自然流产后几天出现阴道出血和头晕，被收治入院。根据她不稳定的病情，进行了子宫切除术。子宫大体病理评估发现多个大而扩张的血管，显微镜下，子宫肌层显示血栓形成，血管壁内有散在的绒毛外滋养细胞。我们描述了这个罕见病例，并探讨了文献，重点是这种情况的病理生理学和有助于诊断的辅助研究。
