Arfuso Frank
School of Dentistry, Oral Health Centre of Western Australia, The University of Western Australia, Nedlands, Australia.
Endothelium. 2006 Sep-Oct;13(5):359-63. doi: 10.1080/10623320600972101.
With the commonly used in vivo animal models of angiogenesis, direct extrapolation of results to the human is not possible. The results presented from this study exemplify various phases of angiogenesis, from cell migration to apoptosis. This supports the use of the dental pulp of the developing human tooth as a viable model of in vivo physiologic angiogenesis.
对于常用的血管生成体内动物模型,无法将结果直接外推至人类。本研究呈现的结果例证了血管生成的各个阶段,从细胞迁移到细胞凋亡。这支持将发育中的人类牙齿的牙髓用作体内生理性血管生成的可行模型。