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麻风病的临床与免疫学特征。

The clinical and immunological features of leprosy.

作者信息

Walker S L, Lockwood D N J

机构信息

Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK.

出版信息

Br Med Bull. 2006;77-78:103-21. doi: 10.1093/bmb/ldl010. Epub 2006 Nov 7.

DOI:10.1093/bmb/ldl010
PMID:17090777
Abstract

Leprosy is a granulomatous disease affecting the skin and nerves caused by Mycobacterium leprae. It continues to be a significant public health problem. Multidrug therapy (MDT) cures the infection, but immunological reactions may occur and neuropathy may lead to disability and deformity. It is important that the manifestations of the condition are recognized as early as possible so that early nerve damage can be identified and treated rapidly.

摘要

麻风病是一种由麻风分枝杆菌引起的、影响皮肤和神经的肉芽肿性疾病。它仍然是一个重大的公共卫生问题。多药联合治疗(MDT)可治愈感染,但可能会发生免疫反应,神经病变可能导致残疾和畸形。尽早识别该病的表现非常重要,以便能够识别早期神经损伤并迅速进行治疗。

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