Lindqvist Pelle G, Marsál Karel, Pirhonen Jouko P
Department of Obstetrics and Gynecology, Clinical Science, Malmö University Hospital, Lund University, Malmö, Sweden.
Acta Obstet Gynecol Scand. 2006;85(11):1299-303. doi: 10.1080/00016340600590014.
Our purpose was to determine normative data for maternal cerebral blood flow indices. Study design. A prospective longitudinal study.
The maternal middle cerebral artery was examined by transcranial Doppler ultrasound in 14 healthy women before (0-10 months prior to conception) and during pregnancy (at 8, 15, 22, 29, and 36 weeks of gestation), and twice after delivery (at 8 and 24 weeks). Middle cerebral artery blood flow velocities were recorded, and pulsatility index and cerebral perfusion pressure were calculated.
Pulsatility index of middle cerebral artery peaked in mid-pregnancy and was constantly increased between 8 and 29 weeks of gestation. The diastolic middle cerebral artery velocity remained fairly constant at about 40 cm/s during the study period, while the systolic velocity peaked at 15 weeks (mean 102 cm/s). Cerebral perfusion pressure dropped to its lowest levels in mid-pregnancy and after delivery.
我们的目的是确定孕妇脑血流指数的标准数据。研究设计：一项前瞻性纵向研究。
对14名健康女性在孕前（受孕前0 - 10个月）、孕期（妊娠8、15、22、29和36周）以及产后两次（产后8周和24周）通过经颅多普勒超声检查其大脑中动脉。记录大脑中动脉血流速度，并计算搏动指数和脑灌注压。
大脑中动脉搏动指数在妊娠中期达到峰值，在妊娠8至29周期间持续升高。在研究期间，大脑中动脉舒张期速度保持在约40 cm/s的相当稳定水平，而收缩期速度在15周时达到峰值（平均102 cm/s）。脑灌注压在妊娠中期和产后降至最低水平。
