Miranda Sandra Regina, Nary Filho Hugo, Padovan Luís Eduardo Marques, Ribeiro Daniel Araki, Nicolielo Daniela, Matsumoto Mariza Akemi
Department of Oral and Maxillofacial Surgery, Universidade do Sagrado Coração - USC, Bauru, São Paulo, Brazil.
Clin Oral Implants Res. 2006 Dec;17(6):694-9. doi: 10.1111/j.1600-0501.2006.01272.x.
To analyze the healing of autogenous onlay bone grafts in three different situations, focusing on the interface area.
Sixteen rabbits underwent autogenous bone graft surgeries in the calvaria. The block bone grafts were positioned in three different situations: direct contact between bone graft and receptor bed, graft interposed by particulate bone, and graft interposed by platelet-rich plasma (PRP). After 7, 15, 30, and 60 days, the specimens were retrieved for histological and morphometric evaluation.
All groups healed uneventfully and presented incorporation of the grafts after 30 days. A slightly more evident new bone formation could be observed in the PRP group in the first analyzed period, and an earlier maturation of bone in the last period, although no statistically significant differences were achieved.
The use of additional material between the bone graft and the receptor bed when using the onlay technique must be carefully considered, taking into account the size of the reconstruction and the cost/benefit relation. The addition of PRP in between autogenous bone blocks and the receptor bed did not confer significant benefit for the new bone formation and healing on the calvaria of bone of rabbits.
分析三种不同情况下自体嵌体骨移植的愈合情况，重点关注界面区域。
16只兔子在颅骨上进行了自体骨移植手术。块状骨移植被放置在三种不同情况下：骨移植与受体床直接接触、移植体由颗粒骨插入、移植体由富血小板血浆（PRP）插入。在7天、15天、30天和60天后，取出标本进行组织学和形态计量学评估。
所有组均顺利愈合，30天后移植体均实现融合。在第一个分析阶段，PRP组可观察到稍更明显的新骨形成，在最后一个阶段骨成熟更早，尽管未达到统计学显著差异。
在使用嵌体技术时，在骨移植和受体床之间使用额外材料必须仔细考虑，要兼顾重建的大小和成本效益关系。在自体骨块和受体床之间添加PRP对兔颅骨上新骨形成和愈合没有显著益处。
