Bell W, Warner J T, Evans W D, Webb D K H, Mullen R H, Gregory J W
University of Wales Institute, Cyncoed, Cardiff, Wales, UK.
Ann Hum Biol. 2006 May-Jun;33(3):357-71. doi: 10.1080/03014460600687382.
The study examined the degree to which male and female survivors of acute lymphoblastic leukaemia (ALL) perceive effort at low and moderate intensity exercise in association with related physiological variables.
Participants were 67 children. Thirty-five (14 boys and 21 girls) were long-time survivors of ALL and 32 (18 boys and 14 girls) were control subjects. The Children's Effort Rating Table (CERT) was used to measure whole-body perceived exertion at low and moderate intensity exercise. Peak oxygen uptake was measured using a motorized treadmill. CERT and physiological data were analysed using 2 x 2 mixed analyses of variance, appropriate t-tests and coefficients of correlation.
In absolute terms, boys treated for ALL found perception of effort to be more strenuous at both low (3.9 vs. 3.5 units) and moderate (6.1 vs. 5.3 units) intensity exercise than control subjects, although differences were not significant (p > 0.05); girls treated for ALL found perception of effort to be the same as controls at low intensity exercise (3.1 vs. 3.1 units) but slightly higher than controls at moderate intensity exercise (5.6 vs. 5.2 units); neither of these differences were significant (p > 0.05). When CERT values were adjusted for (.-)VO(2) peak (%) and heart rate (HR) peak (%) differences remained non-significant. There were no significant interactions (Intensity x Group) in males, but the interaction for (.-)VO(2) peak (%) was significant in females (p < 0.05). The main effect for Intensity (low and moderate) was significant for all variables in boys and girls (p < 0.0001). The main effect for Group (ALL and controls) identified significantly greater absolute (b.p.m.) and relative (%) HR values in ALL boys at low and moderate intensity exercise. In female ALL and control subjects the interaction (Intensity x Group) distinguished between (.-)VO(2) peak (%) at moderate intensity exercise and HR peak (%) at low and moderate intensity exercise. Coefficients of correlation between perceived effort and (.-)VO(2) peak (%) in boys and girls were low to high (0.28-0.76), and between absolute and relative HR were also low to high (0.33-0.73). There were low correlations between time 'off therapy' and perceived effort, (.-)VO(2) peak (%) and HR peak (%) (-0.003 to -0.49).
It was concluded that perception of effort in survivors of ALL at low and moderate intensity exercise was the same as that of control subjects. Correlations between perceived effort and physiological variables at moderate exercise were low to high, while those between perceived effort and time from treatment were generally weak.
本研究调查了急性淋巴细胞白血病（ALL）男性和女性幸存者在低强度和中等强度运动中对运动强度的感知程度，并分析其与相关生理变量之间的关系。
研究对象为67名儿童，其中35名（14名男孩和21名女孩）为ALL长期幸存者，32名（18名男孩和14名女孩）为对照对象。使用儿童运动强度评定量表（CERT）测量低强度和中等强度运动时的全身运动强度感知。使用电动跑步机测量峰值摄氧量。采用2×2混合方差分析、适当的t检验和相关系数对CERT和生理数据进行分析。
从绝对值来看，接受ALL治疗的男孩在低强度（3.9 vs. 3.5单位）和中等强度（6.1 vs. 5.3单位）运动时，感觉运动强度比对照对象更大，尽管差异不显著（p>0.05）；接受ALL治疗的女孩在低强度运动时感觉运动强度与对照对象相同（3.1 vs. 3.1单位），但在中等强度运动时略高于对照对象（5.6 vs. 5.2单位）；这些差异均不显著（p>0.）。调整CERT值以校正峰值摄氧量（.-）VO(2)峰值（%）和心率（HR）峰值（%）后，差异仍然不显著。男性中不存在显著的交互作用（强度×组别），但女性中（.-）VO(2)峰值（%）的交互作用显著（p<0.05）。强度（低强度和中等强度）的主效应在男孩和女孩中对所有变量均显著（p<0.0001）。组别的主效应（ALL和对照）显示，ALL男孩在低强度和中等强度运动时的绝对心率（单位：次/分钟）和相对心率（%）显著更高。在女性ALL患者和对照对象中，交互作用（强度×组别）在中等强度运动时的（.-）VO(2)峰值（%）和低强度及中等强度运动时的HR峰值（%）方面存在差异。男孩和女孩中，运动强度感知与（.-）VO(2)峰值（%）之间的相关系数为低到高（0.28 - 0.76），绝对心率和相对心率之间的相关系数也为低到高（0.33 - 0.73）。“停止治疗时间”与运动强度感知、（.-）VO(2)峰值（%）和HR峰值（%）之间的相关性较低（-0.）。
研究得出结论，ALL幸存者在低强度和中等强度运动时的运动强度感知与对照对象相同。中等强度运动时运动强度感知与生理变量之间的相关性为低到高，而运动强度感知与治疗后时间之间的相关性通常较弱。
