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High incidence of chromosomal abnormalities in oocyte donors.

作者信息

Ravel Célia, Letur Hélène, Le Lannou Dominique, Barthélémy Claire, Bresson Jean Luc, Siffroi Jean Pierre

机构信息

CECOS Paris Tenon, Hôpital Tenon, Paris, France.

出版信息

Fertil Steril. 2007 Feb;87(2):439-41. doi: 10.1016/j.fertnstert.2006.06.053. Epub 2006 Nov 13.

DOI:10.1016/j.fertnstert.2006.06.053
PMID:17094972
Abstract

Oocyte donors are chosen among phenotypically normal and fertile women who are not expected to carry any chromosomal abnormality. A high incidence of balanced structural chromosomal rearrangements has been found within oocyte donors. This result raises the question of a possible bias in their recruitment with respect to their familial background and/or personal reproductive history.

摘要

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