Martines F, Porrello M, Ferrara M, Martines M, Martines E
Università degli Studi di Palermo, Dipartimento di Biotecnologie Mediche e Medicina Legale, Sezione di Audiologia, Italy.
Int J Pediatr Otorhinolaryngol. 2007 Jan;71(1):107-12. doi: 10.1016/j.ijporl.2006.09.011. Epub 2006 Nov 13.
To study the incidence of congenital sensorineural hearing loss in all newborns introducing a screen test with a protocol no expensive, with a good "screen sensitivity" that could let an earlier identification of hearing impairment beginning early intervention by 2 months of age and increasing the probability of having language development within the normal range of development.
The study was conducted in Sciacca hospital from the beginning of 2003 to our days and was carried out with transient evoked otoacoustic emission using the criteria for PASS or RETEST and considering eventual prenatal and perinatal risk factors. All the newborns were divided into four groups each one with its personal secondary step program.
In the years 2003-2004 the number of the newborns in Sciacca hospital was: 538 for 2003, 653 for 2004 with a total of 1191; all these infants were divided in three groups: resident in Sciacca, resident in the Sciacca borderlands and resident out of the district of Sciacca. The coverage (percentage of the target population who undergo the screen) was of 90% in the 2003 (483 newborns) and of 90% in the 2004 (585 newborns) with two cases of congenital sensorineural hearing loss identified. The incidence of sensorineural hearing loss, in the District of Sciacca, was estimated to be 2.07/1000 in 2003 and 1.70/1000 in 2004.
The higher incidence of sensorineural hearing loss in our study is due to a high prevalence of consanguineous marriage in Sicily that was shown to be linked with hearing impairment. The "sensitivity value" was 95% at the first step but became 99% after the second step with a few number of false positive (0.74%). All the infants with a diagnosis of sensorineural hearing loss began a rehabilitation program before the age of 5 months and they have a good speech development and speech intelligibility.
通过引入一种成本不高且具有良好“筛查敏感性”的筛查试验,研究所有新生儿中先天性感音神经性听力损失的发生率,以便能更早地识别听力障碍,在2个月大时开始早期干预,并提高语言发育在正常发育范围内的概率。
该研究于2003年初至现在在锡亚卡医院进行,采用瞬态诱发耳声发射,依据通过或复测标准,并考虑可能的产前和围产期危险因素。所有新生儿被分为四组,每组都有各自的二级检查程序。
2003 - 2004年,锡亚卡医院的新生儿数量为:2003年538例,2004年653例,总计1191例;所有这些婴儿被分为三组:锡亚卡本地居民、锡亚卡边境地区居民和锡亚卡地区以外居民。2003年的筛查覆盖率(接受筛查的目标人群百分比)为90%(483例新生儿),2004年为90%(585例新生儿),共确诊2例先天性感音神经性听力损失。据估计,2003年锡亚卡地区感音神经性听力损失的发生率为2.07/1000,2004年为1.70/1000。
我们研究中感音神经性听力损失的较高发生率是由于西西里岛近亲结婚的高流行率,这已被证明与听力障碍有关。第一步的“敏感性值”为95%,但第二步后变为99%,假阳性数量较少(0.74%)。所有被诊断为感音神经性听力损失的婴儿在5个月龄前开始了康复计划,并且他们有良好的语言发育和言语清晰度。