Solomon Lynn W, Merzianu Mihai, Sullivan Maureen, Rigual Nestor R
Department of Oral Diagnostic Sciences, State University of New York at Buffalo, Buffalo, NY 14214, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Feb;103(2):e39-42. doi: 10.1016/j.tripleo.2006.08.005. Epub 2006 Nov 7.
Necrotizing sialometaplasia (NSM) is a self-limiting disorder affecting mainly the minor salivary glands. The significance of NSM resides in its clinical and histopathological resemblance to carcinoma. Few cases of NSM associated with eating disorders have been reported to date. We present here the clinical features and histomorphology of an additional case of bulimia-associated NSM closely mimicking an invasive carcinoma. A high index of suspicion and good communication between clinician and pathologist are essential in recognizing this entity and preventing unnecessary surgical therapy.
坏死性涎腺化生(NSM)是一种主要影响小涎腺的自限性疾病。NSM的重要性在于其临床和组织病理学表现与癌相似。迄今为止,仅有少数NSM与饮食失调相关的病例报道。我们在此呈现另一例与神经性贪食症相关的NSM的临床特征和组织形态学,该病例酷似浸润性癌。临床医生和病理医生之间保持高度的怀疑指数并进行良好沟通,对于识别该疾病实体及避免不必要的手术治疗至关重要。