Reinhold U
Fachbereich Dermatologie, Allergologie, Dermatologische Onkologie, Medizinisches Zentrum Bonn Friedensplatz, Friedensplatz 16, 53111, Bonn, Germany.
Hautarzt. 2007 Jan;58(1):77-92; quiz 93. doi: 10.1007/s00105-006-1244-2.
Cytostatic chemotherapy is an integral therapeutic concept in dermatological oncology. The cytostatic drugs are mostly used in palliative situations and in most cases can be applied in an outpatient setting. Special medical knowledge as well as organizational structures are necessary for managing ambulant chemotherapy. A broad spectrum of cytostatic drugs is available and their special indications and use for the treatment of different types of dermato-oncological diseases is reviewed. Specific tools have to be taken into account before, during and after the application of chemotherapy. These include prevention of nausea and emesis, safety guidelines related to the prevention of extravasation, as well as special situations related to patient age.
细胞毒性化疗是皮肤肿瘤学中不可或缺的治疗理念。细胞毒性药物大多用于姑息治疗,在大多数情况下可在门诊环境中使用。管理门诊化疗需要专业的医学知识和组织结构。目前有多种细胞毒性药物,本文综述了它们在治疗不同类型皮肤肿瘤疾病中的特殊适应症和用法。在化疗应用前、应用期间和应用后都必须考虑特定的因素。这些因素包括预防恶心和呕吐、预防外渗的安全指南以及与患者年龄相关的特殊情况。