喹喔啉酮和苯并咪唑支架文库的同步固相合成。
Simultaneous solid-phase synthesis of quinoxalinone and benzimidazole scaffold libraries.
作者信息
Kou Bin-Bin, Zhang Fa, Yang Tian-Ming, Liu Gang
机构信息
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 1 Xian Nong Tan Street, Beijing 100050, PR China.
出版信息
J Comb Chem. 2006 Nov-Dec;8(6):841-7. doi: 10.1021/cc060074s.
PMID:17096573
Abstract
This article describes a method for simultaneous solid-phase synthesis of a quinoxalinone and benzimidazole scaffold library that consists of 240 members. The library was generated by using the solid-phase "split-and-pool" approach and the IRORI sorting system.
摘要
本文描述了一种用于同时固相合成由240个成员组成的喹喔啉酮和苯并咪唑支架文库的方法。该文库通过使用固相“拆分与混合”方法和IRORI分选系统生成。
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