Purvis Diana, Robinson Elizabeth, Merry Sally, Watson Peter
Department of Dermatology, Great Ormond Street Hospital for Sick Children, London, United Kingdom.
J Paediatr Child Health. 2006 Dec;42(12):793-6. doi: 10.1111/j.1440-1754.2006.00979.x.
To examine the associations between acne and depressive symptoms, anxiety and suicidal behaviours.
This was a secondary analysis of a cross-sectional survey -'Youth2000' (New Zealand national survey of youth health). A total of 9567 secondary school students aged 12-18 years participated in the survey. The main outcome measures were self-reported acne, depressive symptoms (Reynolds Adolescent Depression Scale > 77), anxiety (Anxiety Disorder Index from Multidimensional Anxiety Scale for Children) and self-reported suicide attempts.
'Problem acne' was associated with an increased probability of depressive symptoms, odds ratio 2.04 (95% confidence interval 1.70-2.45); anxiety, odds ratio 2.3 (1.74-3.00); and suicide attempts, odds ratio 1.83 (1.51-2.22) in a logistic model that included age, gender, ethnicity, school decile and socio-economic status. The association of acne with suicide attempts remained after controlling for depressive symptoms and anxiety, odds ratio 1.50 (1.21-1.86).
Young people presenting with acne are at increased risk of depression, anxiety and suicide attempts. Attention should be paid to their mental health, and the importance of asking directly regarding suicide is emphasised.
探讨痤疮与抑郁症状、焦虑及自杀行为之间的关联。
这是一项对横断面调查“青年2000”（新西兰全国青年健康调查）的二次分析。共有9567名12至18岁的中学生参与了该调查。主要结局指标为自我报告的痤疮、抑郁症状（雷诺兹青少年抑郁量表>77）、焦虑（儿童多维焦虑量表中的焦虑障碍指数）以及自我报告的自杀未遂情况。
在一个包含年龄、性别、种族、学校等级和社会经济地位的逻辑模型中，“重度痤疮”与抑郁症状的发生概率增加相关，比值比为2.04（95%置信区间1.70 - 2.45）；与焦虑相关，比值比为2.3（1.74 - 3.00）；与自杀未遂相关，比值比为1.83（1.51 - 2.22）。在控制了抑郁症状和焦虑后，痤疮与自杀未遂之间的关联仍然存在，比值比为1.50（1.21 - 1.86）。
患有痤疮的年轻人患抑郁症、焦虑症和自杀未遂的风险增加。应关注他们的心理健康，并强调直接询问自杀情况的重要性。
