Grinna L S
Biochim Biophys Acta. 1975 Oct 22;403(2):388-92. doi: 10.1016/0005-2744(75)90067-4.
The temperature dependence of glucose-6-phosphatase (D-glucose-6-phosphate phosphohydrolase EC 3.1.3.9) was studied in rat liver and kidney microsomal fractions. Arrhenius plots were non-linear and showed four distinct discontinuities in enzyme activity over the temperature range 2-41 degrees C. The discontinuities occurred at approx. 39, 30, 20 and 12 degrees C in the liver and were similar to this in the kidney. Changes in the energy of activation for the enzyme were noted at approx. 20 degrees C in both tissues. The multiple discontinuities in glucose-6-phosphatase activity are viewed as a reflection of complex reorganization and/or change in physical state of the membrane components, primarily lipid.
在大鼠肝脏和肾脏微粒体组分中研究了葡萄糖-6-磷酸酶（D-葡萄糖-6-磷酸磷酸水解酶，EC 3.1.3.9）的温度依赖性。阿累尼乌斯曲线是非线性的，并且在2-41摄氏度的温度范围内酶活性出现了四个明显的间断点。这些间断点在肝脏中大约出现在39、30、20和12摄氏度，在肾脏中与之相似。在两种组织中大约20摄氏度时都注意到了该酶活化能的变化。葡萄糖-6-磷酸酶活性的多个间断点被视为膜成分（主要是脂质）复杂重组和/或物理状态变化的反映。
