Davachi Lila
Department of Psychology, Center for Neural Science, 6 Washington Place, Meyer Building, Room 866B, New York University, New York, NY 10003, USA.
Curr Opin Neurobiol. 2006 Dec;16(6):693-700. doi: 10.1016/j.conb.2006.10.012. Epub 2006 Nov 9.
Recent functional imaging work supports the view that item and relational memory depend upon distinct encoding operations within the medial temporal lobe. Specifically, emerging findings demonstrate that the level of engagement of perirhinal cortex predicts later memory for individual items, whereas the level of hippocampal processing correlates with later relational memory, or recovery of additional episodic details. Furthermore, recent functional magnetic resonance imaging evidence in humans suggests that medial temporal lobe cortical input structures, the perirhinal and posterior parahippocampal cortices, differentially participate in the encoding of objects and their context, providing domain-specific input to the hippocampus. Taken together, these data help to construct a working model of how distinct medial temporal lobe structures participate in episodic memory formation with domain-general relational binding mechanisms supported by the hippocampus and provide emerging evidence for domain-specificity within the perirhinal and parahippocampal cortices.
最近的功能成像研究支持这样一种观点，即项目记忆和关系记忆依赖于内侧颞叶内不同的编码操作。具体而言，新出现的研究结果表明，鼻周皮质的参与程度可预测随后对单个项目的记忆，而海马体的处理水平则与随后的关系记忆或额外情节细节的恢复相关。此外，最近人类的功能磁共振成像证据表明，内侧颞叶皮质输入结构，即鼻周皮质和海马旁后皮质，在物体及其背景的编码中发挥不同作用，为海马体提供特定领域的输入。综上所述，这些数据有助于构建一个工作模型，以说明内侧颞叶不同结构如何通过海马体支持的领域通用关系绑定机制参与情景记忆形成，并为鼻周皮质和海马旁皮质内的领域特异性提供新的证据。
