Lee J C, Gupta A, Saifuddin A, Flanagan A, Skinner J A, Briggs T W R, Cannon S R
Department of Radiology, The London Bone and Soft Tissue Tumour Service, London, UK.
Clin Radiol. 2006 Dec;61(12):1029-34. doi: 10.1016/j.crad.2006.05.018.
To describe the preoperative magnetic resonance imaging findings of eight histologically-proven cases of hibernoma.
The site, size, and signal characteristics of eight consecutive hibernomas were retrospectively assessed on T1-weighted spin-echo and short T1 inversion recovery (STIR)/fat-saturated T2-weighted fast spin echo magnetic resonance images. Four patients also had gadolinium-enhanced fat-saturated T1-weighted spin echo imaging. Patient age and sex, and duration of symptoms were recorded.
Three female and five male patients with an average age 36 years (range 16-53 years) were included. Seven lesions occurred in the thigh, four in the anterior compartment and three in the posterior compartment. One lesion occurred superficial to the scapula. All cases demonstrated common magnetic resonance imaging findings of a well-defined, heterogeneous mass, slightly or clearly hypo-intense to subcutaneous fat on T1-weighted spin-echo images, with prominent thin low signal bands throughout the tumour. The lesions failed to fully suppress on STIR or fat-saturated T2-weighted images. Only one of the four contrast-enhanced studies demonstrated increased vascularity in the tumour.
The MRI findings of a lesion that is diffusely slightly hypointense to surrounding subcutaneous fat, should prompt the operator to consider hibernoma in the differential diagnosis.
描述8例经组织学证实的冬眠瘤的术前磁共振成像表现。
回顾性评估8例连续的冬眠瘤在T1加权自旋回波和短T1反转恢复（STIR）/脂肪饱和T2加权快速自旋回波磁共振图像上的部位、大小和信号特征。4例患者还进行了钆增强脂肪饱和T1加权自旋回波成像。记录患者的年龄、性别和症状持续时间。
纳入3例女性和5例男性患者，平均年龄36岁（范围16 - 53岁）。7个病灶位于大腿，4个在前侧间室，3个在后侧间室。1个病灶位于肩胛骨表面。所有病例在磁共振成像上均表现为边界清晰的不均匀肿块，在T1加权自旋回波图像上相对于皮下脂肪呈轻度或明显低信号，肿瘤内可见明显的细低信号带。病灶在STIR或脂肪饱和T2加权图像上未完全抑制。4例增强扫描中只有1例显示肿瘤内血管增多。
病灶在磁共振成像上相对于周围皮下脂肪呈弥漫性轻度低信号的表现，应促使操作者在鉴别诊断时考虑冬眠瘤。
