Vranken Peter, Pogue Michelle, Romalewski Christine, Ratard Raoult
Epidemic Intelligence Service assigned to the Louisiana Office of Public Health, Infectious Disease Epidemiology, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Am J Infect Control. 2006 Nov;34(9):550-4. doi: 10.1016/j.ajic.2006.01.008.
On November 12, 2004, a 5-month-old infant, admitted in the neonatal intensive care unit (NICU) of a Louisiana regional hospital since birth, was diagnosed with pertussis. Measures to prevent further transmission, in the NICU and beyond, were immediately put into place.
Exposed contacts were identified among other patients of the NICU, health care workers, and family members. All were offered pertussis testing and prophylactic treatment.
The source of the outbreak was not identified. Despite the immediate implementation of control measures, a total of 37 additional NICU patients, 198 health care workers, and 15 family members were identified as potentially exposed contacts. Three more infants were diagnosed with pertussis, one of them after having been transferred to the NICU of another hospital in the state.
The source of this outbreak was believed to be an adult, either a hospital worker or an outside visitor. The incident clearly illustrates the infection control challenges for hospital units serving newborns and young infants in an era of changing epidemiology of pertussis.
2004年11月12日，一名自出生起就入住路易斯安那州一家地区医院新生儿重症监护病房（NICU）的5个月大婴儿被诊断患有百日咳。NICU内外立即采取了预防进一步传播的措施。
在NICU的其他患者、医护人员和家庭成员中确定了暴露接触者。所有人员都接受了百日咳检测和预防性治疗。
此次疫情的源头未查明。尽管立即实施了控制措施，但共有37名NICU额外患者、198名医护人员和15名家庭成员被确定为潜在暴露接触者。又有三名婴儿被诊断患有百日咳，其中一名是在转至该州另一家医院的NICU后确诊的。
此次疫情的源头据信是一名成年人，可能是医院工作人员或外部访客。这一事件清楚地说明了在百日咳流行病学不断变化的时代，为新生儿和幼儿提供服务的医院科室在感染控制方面面临的挑战。
