Iyengar Srinivas, Feldman David S, Cooke Glen E, Leier Carl V, Raman Subha V
Division of Cardiovascular Medicine, Ohio State University, Columbus, Ohio 43210, USA.
J Heart Lung Transplant. 2006 Nov;25(11):1363-6. doi: 10.1016/j.healun.2006.06.018. Epub 2006 Sep 8.
Cardiac transplant recipients develop coronary artery disease in the form of cardiac allograft vasculopathy (CAV), and still undergo annual left heart catheterizations for detection at most centers. We prospectively enrolled 20 cardiac transplant recipients scheduled for annual left heart catheterization with X-ray coronary angiography (XRA) to also undergo electrocardiographically gated coronary computed tomography angiography (CTA), which was performed on a 64-detector computed tomography scanner. CTA detected more CAV vs XRA in 4 patients and less CAV in 0 patient, resulting in good overall agreement between the two modalities (kappa = 0.69). CTA may be superior to conventional catheter-based angiography to identify non-obstructive vessel wall disease that may go unrecognized with catheter-based angiography alone.
心脏移植受者会出现心脏移植血管病变（CAV）形式的冠状动脉疾病，并且在大多数中心仍需每年进行左心导管检查以进行检测。我们前瞻性地招募了20名计划进行年度左心导管检查及X线冠状动脉造影（XRA）的心脏移植受者，让他们同时接受心电门控冠状动脉计算机断层扫描血管造影（CTA），该检查在64排计算机断层扫描仪上进行。与XRA相比，CTA在4例患者中检测到更多的CAV，在0例患者中检测到更少的CAV，两种检查方式总体一致性良好（kappa = 0.69）。CTA在识别单独使用基于导管的血管造影可能无法识别的非阻塞性血管壁疾病方面可能优于传统的基于导管的血管造影。
