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宫角妊娠手术治疗后发生进行性宫内双胎妊娠的病例。

Case of progressive intrauterine twin pregnancy after surgical treatment of cornual pregnancy.

作者信息

Divry Véronique, Hadj Samia, Bordes Agnès, Genod Anne, Salle Bruno

机构信息

Département de Médecine de la Reproduction, Hôpital Edouard Herriot, Lyon, France.

出版信息

Fertil Steril. 2007 Jan;87(1):190.e1-3. doi: 10.1016/j.fertnstert.2006.04.053. Epub 2006 Nov 13.

Abstract

OBJECTIVE

To report on a case of heterotopic triplet pregnancy after in utero transfer of three embryos obtained by in vitro fertilization (IVF), with progression of the intrauterine twin pregnancy after resection of the cornual pregnancy.

DESIGN

Technique and instrumentation.

SETTING

Département de Médecine de la Reproduction, Hôpital Edouard Herriot, Lyon, France.

PATIENTS

A 32-year-old woman, nulliparous with primary infertility for the previous 12 years due to mixed causes (tubal and male infertility).

INTERVENTIONS

Diagnosis by ultrasound scan and per-laparoscopic confirmation, followed by resection of the cornual pregnancy by laparotomy.

MAIN OUTCOME MEASURES

Ultrasound diagnosis and follow-up of the pregnancy. Delivery.

RESULTS

Complete ablation of the cornual pregnancy. Progression of the intrauterine twin pregnancy without difficulties until 31 weeks of gestation. Cesarean upon onset of labor. Birth of two living infants. The scar of the uterine horn, examined during the caesarean, was thick and solid.

CONCLUSIONS

The early diagnosis and surgical treatment of an ectopic pregnancy permitted the development of the intrauterine pregnancy. The risk of heterotopic pregnancy is increased by medical techniques that facilitate procreation. This risk is directly related to the number of embryos transferred. In the case of heterotopic pregnancy, the rate of progressive intrauterine pregnancy after treatment of the ectopic pregnancy is encouraging.

摘要

目的

报告一例体外受精(IVF)获取的三个胚胎宫内移植后发生的异位三胎妊娠病例,以及宫角妊娠切除术后宫内双胎妊娠的进展情况。

设计

技术与器械。

地点

法国里昂爱德华·赫里奥特医院生殖医学科。

患者

一名32岁未育女性,因混合因素(输卵管和男性不育)原发性不孕12年。

干预措施

超声扫描诊断及腹腔镜检查确诊,随后行剖腹手术切除宫角妊娠。

主要观察指标

妊娠的超声诊断及随访。分娩情况。

结果

宫角妊娠完全切除。宫内双胎妊娠顺利进展至31周。临产时行剖宫产。两名活婴出生。剖宫产时检查子宫角瘢痕,厚实且坚固。

结论

异位妊娠的早期诊断和手术治疗使宫内妊娠得以发展。辅助生殖技术会增加异位妊娠的风险。这种风险与移植胚胎的数量直接相关。对于异位妊娠,异位妊娠治疗后宫内妊娠进展的比例令人鼓舞。

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