Kuriyan Rebecca, Raj Tony, Srinivas S K, Vaz Mario, Rajendran R, Kurpad Anura V
Division of Nutrition, Institute of Population Health and Clinical Research, St John's National Academy of Health Sciences, Bangalore 560034, India.
Appetite. 2007 May;48(3):338-44. doi: 10.1016/j.appet.2006.09.013. Epub 2006 Nov 13.
Caralluma fimbriata is an edible cactus, used by tribal Indians to suppress hunger and enhance endurance. The effect of Caralluma extract was assessed in overweight individuals by a placebo controlled randomized trial. Fifty adult men and women (25-60 years) with a body mass index (BMI) greater than 25 kg/m2 were randomly assigned into a placebo or experimental group; the latter received 1 g of Caralluma extract per day for 60 days. All subjects were given standard advice regarding a weight reducing diet and physical activity. At the end of 30 and 60 days of intervention, blood glucose and lipids, anthropometric measurements, dietary intake and assessment of appetite was performed. Waist circumference and hunger levels over the observation period showed a significant decline in the experimental group when compared to the placebo group. While there was a trend towards a greater decrease in body weight, body mass index, hip circumference, body fat and energy intake between assessment time points in the experimental group, these were not significantly different between experimental and placebo groups. Caralluma extract appears to suppress appetite, and reduce waist circumference when compared to placebo over a 2 month period.
肉珊瑚是一种可食用的仙人掌，部落印第安人用它来抑制饥饿并增强耐力。通过一项安慰剂对照随机试验评估了肉珊瑚提取物对超重个体的影响。五十名年龄在25至60岁之间、体重指数（BMI）大于25 kg/m² 的成年男性和女性被随机分为安慰剂组或实验组；实验组每天服用1克肉珊瑚提取物，持续60天。所有受试者都得到了关于减肥饮食和体育活动的标准建议。在干预30天和60天结束时，进行了血糖和血脂检测、人体测量、饮食摄入量和食欲评估。与安慰剂组相比，实验组在观察期内的腰围和饥饿水平显著下降。虽然实验组在评估时间点之间体重、体重指数、臀围、体脂和能量摄入有更大幅度下降的趋势，但实验组与安慰剂组之间这些差异并不显著。与安慰剂相比，肉珊瑚提取物在两个月的时间里似乎能抑制食欲并减小腰围。
