Doughan Abdulrahman
Emory University School of Medicine, Cardiology, 1639 Pierce Dr. Suite 319 WMB Atlanta, GA 30322, USA.
Travel Med Infect Dis. 2006 Dec;4(6):332-5. doi: 10.1016/j.tmaid.2006.01.013. Epub 2006 Apr 19.
Disseminated Histoplasmosis is a severe and often-fatal opportunistic infection when left untreated among patients with AIDS. Occurring in 3-5 percent of patients with AIDS living in the areas of endemicity, this infection should be suspected in patients with a CD4 cell count of <150 cells/microL presenting with non-specific clinical signs such as fever, weight loss, and lymphadenopathy. We report our experience to increase awareness of the clinical spectrum of disseminated histoplasmosis and its similarity to other infections and malignancies and update the reader on recommended therapeutic modalities.
播散性组织胞浆菌病是一种严重且往往致命的机会性感染，在艾滋病患者中若不治疗会导致死亡。在组织胞浆菌病流行地区，3%至5%的艾滋病患者会发生这种感染，对于CD4细胞计数低于150个/微升且出现发热、体重减轻和淋巴结病等非特异性临床症状的患者，应怀疑患有这种感染。我们报告我们的经验，以提高对播散性组织胞浆菌病临床谱及其与其他感染和恶性肿瘤相似性的认识，并向读者介绍推荐的治疗方式。
